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Cigarette smoke preferentially induces full length ACE2 expression in differentiated primary human airway cultures but does not alter the efficiency of cellular SARS-CoV-2 infection.
Porter LM, Guo W, Crozier TW, Greenwood EJ, Ortmann B, Kottmann D, Nathan JA, Mahadeva R, Lehner PJ, McCaughan F. Porter LM, et al. Among authors: nathan ja. Heliyon. 2023 Mar;9(3):e14383. doi: 10.1016/j.heliyon.2023.e14383. Epub 2023 Mar 11. Heliyon. 2023. PMID: 36938474 Free PMC article.
A Case of Thrombotic Microangiopathy and Acute Sarcoidosis.
Martinelli AW, Dunn W, McClure ME, Walker I, Stewart A, Karia S, Preston SD, Thiru S, Torpey N, Ojha S, Symington E, Nathan JA. Martinelli AW, et al. Among authors: nathan ja. Chest. 2022 Nov;162(5):e245-e248. doi: 10.1016/j.chest.2022.06.023. Chest. 2022. PMID: 36344132 Free PMC article.
Limited oxygen in standard cell culture alters metabolism and function of differentiated cells.
Tan J, Virtue S, Norris DM, Conway OJ, Yang M, Bidault G, Gribben C, Lugtu F, Kamzolas I, Krycer JR, Mills RJ, Liang L, Pereira C, Dale M, Shun-Shion AS, Baird HJ, Horscroft JA, Sowton AP, Ma M, Carobbio S, Petsalaki E, Murray AJ, Gershlick DC, Nathan JA, Hudson JE, Vallier L, Fisher-Wellman KH, Frezza C, Vidal-Puig A, Fazakerley DJ. Tan J, et al. Among authors: nathan ja. EMBO J. 2024 Apr 5. doi: 10.1038/s44318-024-00084-7. Online ahead of print. EMBO J. 2024. PMID: 38580776 Free article.
Iron dysregulation and inflammatory stress erythropoiesis associates with long-term outcome of COVID-19.
Hanson AL, Mulè MP, Ruffieux H, Mescia F, Bergamaschi L, Pelly VS, Turner L, Kotagiri P; Cambridge Institute of Therapeutic Immunology and Infectious Disease–National Institute for Health Research (CITIID–NIHR) COVID BioResource Collaboration; Göttgens B, Hess C, Gleadall N, Bradley JR, Nathan JA, Lyons PA, Drakesmith H, Smith KGC. Hanson AL, et al. Among authors: nathan ja. Nat Immunol. 2024 Mar;25(3):471-482. doi: 10.1038/s41590-024-01754-8. Epub 2024 Mar 1. Nat Immunol. 2024. PMID: 38429458 Free PMC article.
Glutarate regulates T cell metabolism and anti-tumour immunity.
Minogue E, Cunha PP, Wadsworth BJ, Grice GL, Sah-Teli SK, Hughes R, Bargiela D, Quaranta A, Zurita J, Antrobus R, Velica P, Barbieri L, Wheelock CE, Koivunen P, Nathan JA, Foskolou IP, Johnson RS. Minogue E, et al. Among authors: nathan ja. Nat Metab. 2023 Oct;5(10):1747-1764. doi: 10.1038/s42255-023-00855-2. Epub 2023 Aug 21. Nat Metab. 2023. PMID: 37605057 Free PMC article.
A HIF independent oxygen-sensitive pathway for controlling cholesterol synthesis.
Dickson AS, Pauzaite T, Arnaiz E, Ortmann BM, West JA, Volkmar N, Martinelli AW, Li Z, Wit N, Vitkup D, Kaser A, Lehner PJ, Nathan JA. Dickson AS, et al. Among authors: nathan ja. Nat Commun. 2023 Aug 9;14(1):4816. doi: 10.1038/s41467-023-40541-1. Nat Commun. 2023. PMID: 37558666 Free PMC article.
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