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Structural Optimization and Anticancer Activity of Polo-like Kinase 1 (Plk1) Polo-Box Domain (PBD) Inhibitors and Their Prodrugs.
Park JE, Lee H, Oliva P, Kirsch K, Kim B, Ahn JI, Alverez CN, Gaikwad S, Krausz KW, O'Connor R, Rai G, Simeonov A, Mock BA, Gonzalez FJ, Lee KS, Jacobson KA. Park JE, et al. Among authors: jacobson ka. ACS Pharmacol Transl Sci. 2023 Feb 20;6(3):422-446. doi: 10.1021/acsptsci.2c00250. eCollection 2023 Mar 10. ACS Pharmacol Transl Sci. 2023. PMID: 36926457 Free PMC article.
Metabolic mapping of A3 adenosine receptor agonist MRS5980.
Fang ZZ, Tosh DK, Tanaka N, Wang H, Krausz KW, O'Connor R, Jacobson KA, Gonzalez FJ. Fang ZZ, et al. Among authors: jacobson ka. Biochem Pharmacol. 2015 Sep 15;97(2):215-23. doi: 10.1016/j.bcp.2015.07.007. Epub 2015 Jul 23. Biochem Pharmacol. 2015. PMID: 26212548 Free PMC article.
Peptide-Liganded G Protein-Coupled Receptors as Neurotherapeutics.
Eiden LE, Goosens KA, Jacobson KA, Leggio L, Zhang L. Eiden LE, et al. Among authors: jacobson ka. ACS Pharmacol Transl Sci. 2020 Mar 18;3(2):190-202. doi: 10.1021/acsptsci.0c00017. eCollection 2020 Apr 10. ACS Pharmacol Transl Sci. 2020. PMID: 32296762 Free PMC article. Review.
Adenosine Kinase Expression Determines DNA Methylation in Cancer Cell Lines.
Wahba AE, Fedele D, Gebril H, AlHarfoush E, Toti KS, Jacobson KA, Boison D. Wahba AE, et al. Among authors: jacobson ka. ACS Pharmacol Transl Sci. 2021 Feb 16;4(2):680-686. doi: 10.1021/acsptsci.1c00008. eCollection 2021 Apr 9. ACS Pharmacol Transl Sci. 2021. PMID: 33860193 Free PMC article.
834 results