Ducati RG - Search Results

1

MAT Gain of Activity Mutation in Helicobacter pylori Is Associated with Resistance to MTAN Transition State Analogues.

Feng M, Namanja-Magliano H, Rajagopalan S, Mishra T, Ducati RG, Hirsch BM, Kelly L, Szymczak W, Fajardo JE, Sidoli S, Fiser A, Jacobs WR, Schramm VL. Feng M, et al. Among authors: ducati rg. ACS Infect Dis. 2023 Apr 14;9(4):966-978. doi: 10.1021/acsinfecdis.2c00644. Epub 2023 Mar 15. ACS Infect Dis. 2023. PMID: 36920074 Free PMC article.

2

Transition-state inhibitors of purine salvage and other prospective enzyme targets in malaria.

Ducati RG, Namanja-Magliano HA, Schramm VL. Ducati RG, et al. Future Med Chem. 2013 Jul;5(11):1341-60. doi: 10.4155/fmc.13.51. Future Med Chem. 2013. PMID: 23859211 Free PMC article. Review.

3

Synthesis of bis-Phosphate Iminoaltritol Enantiomers and Structural Characterization with Adenine Phosphoribosyltransferase.

Harris LD, Harijan RK, Ducati RG, Evans GB, Hirsch BM, Schramm VL. Harris LD, et al. Among authors: ducati rg. ACS Chem Biol. 2018 Jan 19;13(1):152-160. doi: 10.1021/acschembio.7b00601. Epub 2017 Dec 14. ACS Chem Biol. 2018. PMID: 29178779 Free PMC article.

4

Genetic resistance to purine nucleoside phosphorylase inhibition in Plasmodium falciparum.

Ducati RG, Namanja-Magliano HA, Harijan RK, Fajardo JE, Fiser A, Daily JP, Schramm VL. Ducati RG, et al. Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):2114-2119. doi: 10.1073/pnas.1525670115. Epub 2018 Feb 12. Proc Natl Acad Sci U S A. 2018. PMID: 29440412 Free PMC article.

5

Transition-State Analogues of Campylobacter jejuni 5'-Methylthioadenosine Nucleosidase.

Ducati RG, Harijan RK, Cameron SA, Tyler PC, Evans GB, Schramm VL. Ducati RG, et al. ACS Chem Biol. 2018 Nov 16;13(11):3173-3183. doi: 10.1021/acschembio.8b00781. Epub 2018 Oct 19. ACS Chem Biol. 2018. PMID: 30339406 Free PMC article.

6

Selective Inhibitors of Helicobacter pylori Methylthioadenosine Nucleosidase and Human Methylthioadenosine Phosphorylase.

Harijan RK, Hoff O, Ducati RG, Firestone RS, Hirsch BM, Evans GB, Schramm VL, Tyler PC. Harijan RK, et al. Among authors: ducati rg. J Med Chem. 2019 Apr 11;62(7):3286-3296. doi: 10.1021/acs.jmedchem.8b01642. Epub 2019 Mar 28. J Med Chem. 2019. PMID: 30860833 Free PMC article.

7

Antibacterial Strategy against H. pylori: Inhibition of the Radical SAM Enzyme MqnE in Menaquinone Biosynthesis.

Joshi S, Fedoseyenko D, Mahanta N, Ducati RG, Feng M, Schramm VL, Begley TP. Joshi S, et al. Among authors: ducati rg. ACS Med Chem Lett. 2019 Feb 15;10(3):363-366. doi: 10.1021/acsmedchemlett.8b00649. eCollection 2019 Mar 14. ACS Med Chem Lett. 2019. PMID: 30891141 Free PMC article.

8

Kinetic Isotope Effects and Transition State Structure for Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase from Plasmodium falciparum.

Ducati RG, Firestone RS, Schramm VL. Ducati RG, et al. Biochemistry. 2017 Dec 5;56(48):6368-6376. doi: 10.1021/acs.biochem.7b01027. Epub 2017 Nov 21. Biochemistry. 2017. PMID: 29131588 Free PMC article.

9

Continuous Fluorescence Assays for Reactions Involving Adenine.

Firestone RS, Cameron SA, Tyler PC, Ducati RG, Spitz AZ, Schramm VL. Firestone RS, et al. Among authors: ducati rg. Anal Chem. 2016 Dec 6;88(23):11860-11867. doi: 10.1021/acs.analchem.6b03621. Epub 2016 Nov 11. Anal Chem. 2016. PMID: 27779859 Free PMC article.

10

Inhibition and Mechanism of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase.

V T Minnow Y, Suthagar K, Clinch K, Ducati RG, Ghosh A, Buckler JN, Harijan RK, Cahill SM, Tyler PC, Schramm VL. V T Minnow Y, et al. Among authors: ducati rg. ACS Chem Biol. 2022 Dec 16;17(12):3407-3419. doi: 10.1021/acschembio.2c00546. Epub 2022 Nov 22. ACS Chem Biol. 2022. PMID: 36413975 Free PMC article.

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