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Mucus polymer concentration and in vivo adaptation converge to define the antibiotic response of Pseudomonas aeruginosa during chronic lung infection.
Greenwald MA, Meinig SL, Plott LM, Roca C, Higgs MG, Vitko NP, Markovetz MR, Rouillard KR, Carpenter J, Kesimer M, Hill DB, Schisler JC, Wolfgang MC. Greenwald MA, et al. Among authors: higgs mg. bioRxiv [Preprint]. 2023 Dec 21:2023.12.20.572620. doi: 10.1101/2023.12.20.572620. bioRxiv. 2023. PMID: 38187602 Free PMC article. Updated. Preprint.
Mucus polymer concentration and in vivo adaptation converge to define the antibiotic response of Pseudomonas aeruginosa during chronic lung infection.
Greenwald MA, Meinig SL, Plott LM, Roca C, Higgs MG, Vitko NP, Markovetz MR, Rouillard KR, Carpenter J, Kesimer M, Hill DB, Schisler JC, Wolfgang MC. Greenwald MA, et al. Among authors: higgs mg. mBio. 2024 Apr 23:e0345123. doi: 10.1128/mbio.03451-23. Online ahead of print. mBio. 2024. PMID: 38651896 Free article.
Nlrp3 Increases the Host's Susceptibility to Tularemia.
Suresh RV, Bradley EW, Higgs M, Russo VC, Alqahtani M, Huang W, Bakshi CS, Malik M. Suresh RV, et al. Front Microbiol. 2021 Oct 6;12:725572. doi: 10.3389/fmicb.2021.725572. eCollection 2021. Front Microbiol. 2021. PMID: 34690967 Free PMC article.
Atypical PKC, PKCλ/ι, activates β-secretase and increases Aβ1-40/42 and phospho-tau in mouse brain and isolated neuronal cells, and may link hyperinsulinemia and other aPKC activators to development of pathological and memory abnormalities in Alzheimer's disease.
Sajan MP, Hansen BC, Higgs MG, Kahn CR, Braun U, Leitges M, Park CR, Diamond DM, Farese RV. Sajan MP, et al. Among authors: higgs mg. Neurobiol Aging. 2018 Jan;61:225-237. doi: 10.1016/j.neurobiolaging.2017.09.001. Epub 2017 Sep 15. Neurobiol Aging. 2018. PMID: 29032894 Free PMC article.