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Multifaceted role for p53 in pancreatic cancer suppression.
Proc Natl Acad Sci U S A. 2023 Mar 7;120(10):e2211937120. doi: 10.1073/pnas.2211937120. Epub 2023 Feb 27.
Proc Natl Acad Sci U S A. 2023.
PMID: 36848578
Free PMC article.
Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells.
Lee J, Snyder ER, Liu Y, Gu X, Wang J, Flowers BM, Kim YJ, Park S, Szot GL, Hruban RH, Longacre TA, Kim SK.
Lee J, et al. Among authors: flowers bm.
Nat Commun. 2017 Mar 8;8:14686. doi: 10.1038/ncomms14686.
Nat Commun. 2017.
PMID: 28272465
Free PMC article.
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A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer.
Mello SS, Valente LJ, Raj N, Seoane JA, Flowers BM, McClendon J, Bieging-Rolett KT, Lee J, Ivanochko D, Kozak MM, Chang DT, Longacre TA, Koong AC, Arrowsmith CH, Kim SK, Vogel H, Wood LD, Hruban RH, Curtis C, Attardi LD.
Mello SS, et al. Among authors: flowers bm.
Cancer Cell. 2017 Oct 9;32(4):460-473.e6. doi: 10.1016/j.ccell.2017.09.007.
Cancer Cell. 2017.
PMID: 29017057
Free PMC article.
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Cell of Origin Influences Pancreatic Cancer Subtype.
Flowers BM, Xu H, Mulligan AS, Hanson KJ, Seoane JA, Vogel H, Curtis C, Wood LD, Attardi LD.
Flowers BM, et al.
Cancer Discov. 2021 Mar;11(3):660-677. doi: 10.1158/2159-8290.CD-20-0633.
Cancer Discov. 2021.
PMID: 34009137
Free PMC article.
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Epigenetic priming targets tumor heterogeneity to shift transcriptomic phenotype of pancreatic ductal adenocarcinoma towards a Vitamin D susceptible state.
He B, Stoffel L, He CJ, Cho K, Li AM, Jiang H, Flowers BM, Nguyen KT, Wang KW, Zhao AY, Zhou MN, Ferreira S, Attardi LD, Ye J.
He B, et al. Among authors: flowers bm.
Cell Death Dis. 2024 Jan 26;15(1):89. doi: 10.1038/s41419-024-06460-9.
Cell Death Dis. 2024.
PMID: 38272889
Free PMC article.
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RAS induced senescence of skin keratinocytes is mediated through Rho-associated protein kinase (ROCK).
Lee AJ, Fraser E, Flowers B, Kim J, Wong K, Cataisson C, Liu H, Yang H, Lee MP, Yuspa SH, Li L.
Lee AJ, et al.
Mol Carcinog. 2021 Dec;60(12):799-812. doi: 10.1002/mc.23351. Epub 2021 Sep 17.
Mol Carcinog. 2021.
PMID: 34534377
Free PMC article.
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MK-STYX Alters the Morphology of Primary Neurons, and Outgrowths in MK-STYX Overexpressing PC-12 Cells Develop a Neuronal Phenotype.
Banks DA, Dahal A, McFarland AG, Flowers BM, Stephens CA, Swack B, Gugssa A, Anderson WA, Hinton SD.
Banks DA, et al. Among authors: flowers bm.
Front Mol Biosci. 2017 Nov 16;4:76. doi: 10.3389/fmolb.2017.00076. eCollection 2017.
Front Mol Biosci. 2017.
PMID: 29250526
Free PMC article.
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The pseudophosphatase MK-STYX induces neurite-like outgrowths in PC12 cells.
Flowers BM, Rusnak LE, Wong KE, Banks DA, Munyikwa MR, McFarland AG, Hinton SD.
Flowers BM, et al.
PLoS One. 2014 Dec 5;9(12):e114535. doi: 10.1371/journal.pone.0114535. eCollection 2014.
PLoS One. 2014.
PMID: 25479605
Free PMC article.
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