Gadd SL - Search Results

1

Novel genetically engineered H3.3G34R model reveals cooperation with ATRX loss in upregulation of Hoxa cluster genes and promotion of neuronal lineage.

Abdallah AS, Cardona HJ, Gadd SL, Brat DJ, Powla PP, Alruwalli WS, Shen C, Picketts DJ, Li XN, Becher OJ. Abdallah AS, et al. Among authors: gadd sl. Neurooncol Adv. 2023 Jan 6;5(1):vdad003. doi: 10.1093/noajnl/vdad003. eCollection 2023 Jan-Dec. Neurooncol Adv. 2023. PMID: 36845293 Free PMC article.

2

ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis.

Hoeman CM, Cordero FJ, Hu G, Misuraca K, Romero MM, Cardona HJ, Nazarian J, Hashizume R, McLendon R, Yu P, Procissi D, Gadd S, Becher OJ. Hoeman CM, et al. Nat Commun. 2019 Mar 4;10(1):1023. doi: 10.1038/s41467-019-08823-9. Nat Commun. 2019. PMID: 30833574 Free PMC article.

3

Prenatal overexpression of platelet-derived growth factor receptor A results in central nervous system hypomyelination.

Cardona HJ, Somasundaram A, Crabtree DM, Gadd SL, Becher OJ. Cardona HJ, et al. Among authors: gadd sl. Brain Behav. 2021 Oct;11(10):e2332. doi: 10.1002/brb3.2332. Epub 2021 Sep 4. Brain Behav. 2021. PMID: 34480532 Free PMC article.

4

A tumor suppressor role for EZH2 in diffuse midline glioma pathogenesis.

Dhar S, Gadd S, Patel P, Vaynshteyn J, Raju GP, Hashizume R, Brat DJ, Becher OJ. Dhar S, et al. Acta Neuropathol Commun. 2022 Apr 8;10(1):47. doi: 10.1186/s40478-022-01336-5. Acta Neuropathol Commun. 2022. PMID: 35395831 Free PMC article.

5

A novel mouse model of diffuse midline glioma initiated in neonatal oligodendrocyte progenitor cells highlights cell-of-origin dependent effects of H3K27M.

Tomita Y, Shimazu Y, Somasundaram A, Tanaka Y, Takata N, Ishi Y, Gadd S, Hashizume R, Angione A, Pinero G, Hambardzumyan D, Brat DJ, Hoeman CM, Becher OJ. Tomita Y, et al. Glia. 2022 Sep;70(9):1681-1698. doi: 10.1002/glia.24189. Epub 2022 May 7. Glia. 2022. PMID: 35524725 Free PMC article.

6

BET bromodomain inhibition potentiates radiosensitivity in models of H3K27-altered diffuse midline glioma.

Watanabe J, Clutter MR, Gullette MJ, Sasaki T, Uchida E, Kaur S, Mo Y, Abe K, Ishi Y, Takata N, Natsumeda M, Gadd S, Zhang Z, Becher OJ, Hashizume R. Watanabe J, et al. J Clin Invest. 2024 May 21:e174794. doi: 10.1172/JCI174794. Online ahead of print. J Clin Invest. 2024. PMID: 38771655 Free article.

7

A unique subset of low-risk Wilms tumors is characterized by loss of function of TRIM28 (KAP1), a gene critical in early renal development: A Children's Oncology Group study.

Armstrong AE, Gadd S, Huff V, Gerhard DS, Dome JS, Perlman EJ. Armstrong AE, et al. PLoS One. 2018 Dec 13;13(12):e0208936. doi: 10.1371/journal.pone.0208936. eCollection 2018. PLoS One. 2018. PMID: 30543698 Free PMC article.

8

Significance of TP53 Mutation in Wilms Tumors with Diffuse Anaplasia: A Report from the Children's Oncology Group.

Ooms AH, Gadd S, Gerhard DS, Smith MA, Guidry Auvil JM, Meerzaman D, Chen QR, Hsu CH, Yan C, Nguyen C, Hu Y, Ma Y, Zong Z, Mungall AJ, Moore RA, Marra MA, Huff V, Dome JS, Chi YY, Tian J, Geller JI, Mullighan CG, Ma J, Wheeler DA, Hampton OA, Walz AL, van den Heuvel-Eibrink MM, de Krijger RR, Ross N, Gastier-Foster JM, Perlman EJ. Ooms AH, et al. Clin Cancer Res. 2016 Nov 15;22(22):5582-5591. doi: 10.1158/1078-0432.CCR-16-0985. Epub 2016 Oct 4. Clin Cancer Res. 2016. PMID: 27702824 Free PMC article.

9

Polo-Like Kinase 4 (PLK4) Is Overexpressed in Central Nervous System Neuroblastoma (CNS-NB).

Bailey AW, Suri A, Chou PM, Pundy T, Gadd S, Raimondi SL, Tomita T, Sredni ST. Bailey AW, et al. Among authors: gadd s. Bioengineering (Basel). 2018 Nov 4;5(4):96. doi: 10.3390/bioengineering5040096. Bioengineering (Basel). 2018. PMID: 30400339 Free PMC article.

10

Rhabdoid tumor: gene expression clues to pathogenesis and potential therapeutic targets.

Gadd S, Sredni ST, Huang CC, Perlman EJ; Renal Tumor Committee of the Children's Oncology Group. Gadd S, et al. Lab Invest. 2010 May;90(5):724-38. doi: 10.1038/labinvest.2010.66. Epub 2010 Mar 8. Lab Invest. 2010. PMID: 20212451 Free PMC article.

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