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Investigation of the Adrenergic and Opioid Binding Affinities, Metabolic Stability, Plasma Protein Binding Properties, and Functional Effects of Selected Indole-Based Kratom Alkaloids.
Obeng S, Kamble SH, Reeves ME, Restrepo LF, Patel A, Behnke M, Chear NJ, Ramanathan S, Sharma A, León F, Hiranita T, Avery BA, McMahon LR, McCurdy CR. Obeng S, et al. Among authors: kamble sh. J Med Chem. 2020 Jan 9;63(1):433-439. doi: 10.1021/acs.jmedchem.9b01465. Epub 2019 Dec 27. J Med Chem. 2020. PMID: 31834797 Free PMC article.
Pharmacokinetic and Pharmacodynamic Consequences of Cytochrome P450 3A Inhibition on Mitragynine Metabolism in Rats.
Kamble SH, Obeng S, León F, Restrepo LF, King TI, Berthold EC, Kanumuri SRR, Gamez-Jimenez LR, Pallares VLC, Patel A, Ho NP, Hampson A, McCurdy CR, McMahon LR, Wilkerson JL, Sharma A, Hiranita T. Kamble SH, et al. J Pharmacol Exp Ther. 2023 Jun;385(3):180-192. doi: 10.1124/jpet.122.001525. Epub 2023 Apr 5. J Pharmacol Exp Ther. 2023. PMID: 37019472 Free PMC article.
Simultaneous quantification of ten key Kratom alkaloids in Mitragyna speciosa leaf extracts and commercial products by ultra-performance liquid chromatography-tandem mass spectrometry.
Sharma A, Kamble SH, León F, Chear NJ, King TI, Berthold EC, Ramanathan S, McCurdy CR, Avery BA. Sharma A, et al. Among authors: kamble sh. Drug Test Anal. 2019 Aug;11(8):1162-1171. doi: 10.1002/dta.2604. Epub 2019 May 15. Drug Test Anal. 2019. PMID: 30997725 Free PMC article.
UPLC-MS/MS method for the quantification of MCI-77, a novel sigma-1 receptor ligand, and its application to pharmacokinetic studies.
Popa R, Kamble SH, Kanumuri RS, King TI, Berthold EC, Intagliata S, Sharma A, McCurdy CR. Popa R, et al. Among authors: kamble sh. J Chromatogr B Analyt Technol Biomed Life Sci. 2022 Apr 30;1196:123187. doi: 10.1016/j.jchromb.2022.123187. Epub 2022 Mar 5. J Chromatogr B Analyt Technol Biomed Life Sci. 2022. PMID: 35278810 Free PMC article.
27 results