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Structural Optimization of siRNA Conjugates for Albumin Binding Achieves Effective MCL1-Targeted Cancer Therapy.
Hoogenboezem EN, Patel SS, Cavnar AB, Lo JH, Babb LM, Francini N, Patil P, Colazo JM, Michell DL, Sanchez VM, McCune JT, Ma J, DeJulius CR, Lee LH, Rosch JC, Allen RM, Stokes LD, Hill JL, Vickers KC, Cook RS, Duvall CL. Hoogenboezem EN, et al. Among authors: duvall cl. bioRxiv [Preprint]. 2023 Feb 15:2023.02.14.528574. doi: 10.1101/2023.02.14.528574. bioRxiv. 2023. PMID: 36824780 Free PMC article. Updated. Preprint.
Selective mTORC2 Inhibitor Therapeutically Blocks Breast Cancer Cell Growth and Survival.
Werfel TA, Wang S, Jackson MA, Kavanaugh TE, Joly MM, Lee LH, Hicks DJ, Sanchez V, Ericsson PG, Kilchrist KV, Dimobi SC, Sarett SM, Brantley-Sieders DM, Cook RS, Duvall CL. Werfel TA, et al. Among authors: duvall cl. Cancer Res. 2018 Apr 1;78(7):1845-1858. doi: 10.1158/0008-5472.CAN-17-2388. Epub 2018 Jan 22. Cancer Res. 2018. PMID: 29358172 Free PMC article.
Harnessing albumin as a carrier for cancer therapies.
Hoogenboezem EN, Duvall CL. Hoogenboezem EN, et al. Among authors: duvall cl. Adv Drug Deliv Rev. 2018 May;130:73-89. doi: 10.1016/j.addr.2018.07.011. Epub 2018 Jul 27. Adv Drug Deliv Rev. 2018. PMID: 30012492 Free PMC article. Review.
Dual carrier-cargo hydrophobization and charge ratio optimization improve the systemic circulation and safety of zwitterionic nano-polyplexes.
Jackson MA, Bedingfield SK, Yu F, Stokan ME, Miles RE, Curvino EJ, Hoogenboezem EN, Bonami RH, Patel SS, Kendall PL, Giorgio TD, Duvall CL. Jackson MA, et al. Among authors: duvall cl. Biomaterials. 2019 Feb;192:245-259. doi: 10.1016/j.biomaterials.2018.11.010. Epub 2018 Nov 10. Biomaterials. 2019. PMID: 30458360 Free PMC article.
An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles.
Evans BC, Fletcher RB, Kilchrist KV, Dailing EA, Mukalel AJ, Colazo JM, Oliver M, Cheung-Flynn J, Brophy CM, Tierney JW, Isenberg JS, Hankenson KD, Ghimire K, Lander C, Gersbach CA, Duvall CL. Evans BC, et al. Among authors: duvall cl. Nat Commun. 2019 Nov 1;10(1):5012. doi: 10.1038/s41467-019-12906-y. Nat Commun. 2019. PMID: 31676764 Free PMC article.
128 results