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Page 1
The coherence of synthetic telomeres.
Acevedo OL, Dickinson LA, Macke TJ, Thomas CA Jr. Acevedo OL, et al. Nucleic Acids Res. 1991 Jun 25;19(12):3409-19. doi: 10.1093/nar/19.12.3409. Nucleic Acids Res. 1991. PMID: 1648206 Free PMC article.
3-[(2R)-Amino-2-phenylethyl]-1-(2,6-difluorobenzyl)-5-(2-fluoro-3-methoxyphenyl)- 6-methylpyrimidin-2,4-dione (NBI 42902) as a potent and orally active antagonist of the human gonadotropin-releasing hormone receptor. Design, synthesis, and in vitro and in vivo characterization.
Tucci FC, Zhu YF, Struthers RS, Guo Z, Gross TD, Rowbottom MW, Acevedo O, Gao Y, Saunders J, Xie Q, Reinhart GJ, Liu XJ, Ling N, Bonneville AK, Chen T, Bozigian H, Chen C. Tucci FC, et al. J Med Chem. 2005 Feb 24;48(4):1169-78. doi: 10.1021/jm049218c. J Med Chem. 2005. PMID: 15715483
Synthesis and structure-activity relationships of uracil derived human GnRH receptor antagonists: (R)-3-[2-(2-amino)phenethyl]-1-(2,6-difluorobenzyl)-6-methyluracils containing a substituted thiophene or thiazole at C-5.
Rowbottom MW, Tucci FC, Connors PJ Jr, Gross TD, Zhu YF, Guo Z, Moorjani M, Acevedo O, Carter L, Sullivan SK, Xie Q, Fisher A, Struthers RS, Saunders J, Chen C. Rowbottom MW, et al. Bioorg Med Chem Lett. 2004 Oct 4;14(19):4967-73. doi: 10.1016/j.bmcl.2004.07.022. Bioorg Med Chem Lett. 2004. PMID: 15341961
Drug leads from combinatorial phosphodiester libraries.
Davis PW, Vickers TA, Wilson-Lingardo L, Wyatt JR, Guinosso CJ, Sanghvi YS, DeBaets EA, Acevedo OL, Cook PD, Ecker DJ. Davis PW, et al. Among authors: acevedo ol. J Med Chem. 1995 Oct 27;38(22):4363-6. doi: 10.1021/jm00022a002. J Med Chem. 1995. PMID: 7473564 No abstract available.
13 results