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Exploiting the intrinsic misfolding propensity of the KRAS oncoprotein.
Janssen K, Claes F, Van de Velde D, Wehbi VL, Houben B, Lampi Y, Nys M, Khodaparast L, Khodaparast L, Louros N, van der Kant R, Verniers J, Garcia T, Ramakers M, Konstantoulea K, Maragkou K, Duran-Romaña R, Musteanu M, Barbacid M, Scorneaux B, Beirnaert E, Schymkowitz J, Rousseau F. Janssen K, et al. Among authors: nys m. Proc Natl Acad Sci U S A. 2023 Feb 28;120(9):e2214921120. doi: 10.1073/pnas.2214921120. Epub 2023 Feb 22. Proc Natl Acad Sci U S A. 2023. PMID: 36812200 Free PMC article.
The structural basis for an on-off switch controlling Gβγ-mediated inhibition of TRPM3 channels.
Behrendt M, Gruss F, Enzeroth R, Dembla S, Zhao S, Crassous PA, Mohr F, Nys M, Louros N, Gallardo R, Zorzini V, Wagner D, Economou A, Rousseau F, Schymkowitz J, Philipp SE, Rohacs T, Ulens C, Oberwinkler J. Behrendt M, et al. Among authors: nys m. Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):29090-29100. doi: 10.1073/pnas.2001177117. Epub 2020 Oct 29. Proc Natl Acad Sci U S A. 2020. PMID: 33122432 Free PMC article.
Sustained Remission and Outcomes with Abatacept plus Methotrexate Following Stepwise Dose De-escalation in Patients with Early Rheumatoid Arthritis.
Emery P, Tanaka Y, Bykerk VP, Huizinga TWJ, Citera G, Bingham CO 3rd, Banerjee S, Soule BP, Nys M, Connolly SE, Lozenski KL, Zhuo J, Wong R, Huang KG, Fleischmann R. Emery P, et al. Among authors: nys m. Rheumatol Ther. 2023 Jun;10(3):707-727. doi: 10.1007/s40744-022-00519-9. Epub 2023 Mar 3. Rheumatol Ther. 2023. PMID: 36869251 Free PMC article.
79 results