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Methods for the isolation and analysis of Aβ from postmortem brain.
Front Neurosci. 2023 Jan 26;17:1108715. doi: 10.3389/fnins.2023.1108715. eCollection 2023.
Front Neurosci. 2023.
PMID: 36777642
Free PMC article.
PrP-grafted antibodies bind certain amyloid β-protein aggregates, but do not prevent toxicity.
Mengel D, Hong W, Corbett GT, Liu W, DeSousa A, Solforosi L, Fang C, Frosch MP, Collinge J, Harris DA, Walsh DM.
Mengel D, et al.
Brain Res. 2019 May 1;1710:125-135. doi: 10.1016/j.brainres.2018.12.038. Epub 2018 Dec 26.
Brain Res. 2019.
PMID: 30593771
Free PMC article.
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PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins.
Corbett GT, Wang Z, Hong W, Colom-Cadena M, Rose J, Liao M, Asfaw A, Hall TC, Ding L, DeSousa A, Frosch MP, Collinge J, Harris DA, Perkinton MS, Spires-Jones TL, Young-Pearse TL, Billinton A, Walsh DM.
Corbett GT, et al.
Acta Neuropathol. 2020 Mar;139(3):503-526. doi: 10.1007/s00401-019-02114-9. Epub 2019 Dec 18.
Acta Neuropathol. 2020.
PMID: 31853635
Free PMC article.
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Laboratory evolution of a sortase enzyme that modifies amyloid-β protein.
Podracky CJ, An C, DeSousa A, Dorr BM, Walsh DM, Liu DR.
Podracky CJ, et al.
Nat Chem Biol. 2021 Mar;17(3):317-325. doi: 10.1038/s41589-020-00706-1. Epub 2021 Jan 11.
Nat Chem Biol. 2021.
PMID: 33432237
Free PMC article.
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