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Heterogeneity in the half-life of factor VIII concentrate in patients with hemophilia A is due to variability in the clearance of endogenous von Willebrand factor.
Elsheikh E, Lavin M, Heck LA, Larkin N, Mullaney B, Doherty D, Kennedy M, Keenan C, Guest T, O'Mahony B, Fazavana J, Fallon PG, Preston RJS, Gormley J, Ryan K, O'Connell NM, Singleton E, Byrne M, McGowan M, Roche S, Doyle M, Crowley MP, O'Shea SI, Reipert BM, Johnsen JM, Pipe SW, Di Paola J, Turecek PL, O'Donnell JS; iPATH study group. Elsheikh E, et al. Among authors: fazavana j. J Thromb Haemost. 2023 May;21(5):1123-1134. doi: 10.1016/j.jtha.2023.01.013. Epub 2023 Jan 20. J Thromb Haemost. 2023. PMID: 36775768 Free article.
The von Willebrand factor - ADAMTS-13 axis in malaria.
O'Donnell AS, Fazavana J, O'Donnell JS. O'Donnell AS, et al. Among authors: fazavana j. Res Pract Thromb Haemost. 2022 Feb 1;6(1):e12641. doi: 10.1002/rth2.12641. eCollection 2022 Jan. Res Pract Thromb Haemost. 2022. PMID: 35128300 Free PMC article.
Persistent endotheliopathy in the pathogenesis of long COVID syndrome.
Fogarty H, Townsend L, Morrin H, Ahmad A, Comerford C, Karampini E, Englert H, Byrne M, Bergin C, O'Sullivan JM, Martin-Loeches I, Nadarajan P, Bannan C, Mallon PW, Curley GF, Preston RJS, Rehill AM, McGonagle D, Ni Cheallaigh C, Baker RI, Renné T, Ward SE, O'Donnell JS; Irish COVID-19 Vasculopathy Study (iCVS) investigators. Fogarty H, et al. J Thromb Haemost. 2021 Oct;19(10):2546-2553. doi: 10.1111/jth.15490. Epub 2021 Sep 12. J Thromb Haemost. 2021. PMID: 34375505 Free PMC article.
Sustained VWF-ADAMTS-13 axis imbalance and endotheliopathy in long COVID syndrome is related to immune dysfunction.
Fogarty H, Ward SE, Townsend L, Karampini E, Elliott S, Conlon N, Dunne J, Kiersey R, Naughton A, Gardiner M, Byrne M, Bergin C, O'Sullivan JM, Martin-Loeches I, Nadarajan P, Bannan C, Mallon PW, Curley GF, Preston RJS, Rehill AM, Baker RI, Cheallaigh CN, O'Donnell JS; Irish COVID-19 Vasculopathy Study (iCVS) Investigators. Fogarty H, et al. J Thromb Haemost. 2022 Oct;20(10):2429-2438. doi: 10.1111/jth.15830. Epub 2022 Aug 4. J Thromb Haemost. 2022. PMID: 35875995 Free PMC article.
Macrophage Galactose Lectin Contributes to the Regulation of FVIII (Factor VIII) Clearance in Mice-Brief Report.
Ward SE, Guest T, Byrne C, Lopes P, O'Sullivan JM, Doherty D, O'Connell D, Gutierrez Llaneza S, Chion A, Fazavana J, Fallon PG, Preston RJS, Johnsen JM, Pipe SW, Turecek PL, O'Donnell JS; iPATH Study Group. Ward SE, et al. Among authors: fazavana j. Arterioscler Thromb Vasc Biol. 2023 Apr;43(4):540-546. doi: 10.1161/ATVBAHA.122.317807. Epub 2023 Feb 2. Arterioscler Thromb Vasc Biol. 2023. PMID: 36727518 Free PMC article.
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