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Fatty acid acylated peptide therapeutics: discovery of omega-n oxidation of the lipid chain as a novel metabolic pathway in preclinical species.
Esposito S, Krick A, Pasquier O, Bonche F, Ingenito R, Magotti P, Bianchi E, Monteagudo E, Gallo M, Cicero DO, Orsatti L, Veneziano M, Caretti F, Mele R, Roversi D, Gennari N, Brasseur D, Gauzy-Lazo L, Duclos O, Mauriac C, Illiano S, Mallart S. Esposito S, et al. Among authors: orsatti l. J Pharm Biomed Anal. 2023 Apr 1;227:115256. doi: 10.1016/j.jpba.2023.115256. Epub 2023 Jan 18. J Pharm Biomed Anal. 2023. PMID: 36764268
A single-run liquid chromatography mass spectrometry method to quantify neuroactive kynurenine pathway metabolites in rat plasma.
Orsatti L, Speziale R, Orsale MV, Caretti F, Veneziano M, Zini M, Monteagudo E, Lyons K, Beconi M, Chan K, Herbst T, Toledo-Sherman L, Munoz-Sanjuan I, Bonelli F, Dominguez C. Orsatti L, et al. J Pharm Biomed Anal. 2015 Mar 25;107:426-31. doi: 10.1016/j.jpba.2015.01.030. Epub 2015 Jan 24. J Pharm Biomed Anal. 2015. PMID: 25668794
Identification of Potent and Long-Acting Single-Chain Peptide Mimetics of Human Relaxin-2 for Cardiovascular Diseases.
Mallart S, Ingenito R, Bianchi E, Bresciani A, Esposito S, Gallo M, Magotti P, Monteagudo E, Orsatti L, Roversi D, Santoprete A, Tucci F, Veneziano M, Bartsch R, Boehm C, Brasseur D, Bruneau P, Corbier A, Froissant J, Gauzy-Lazo L, Gervat V, Marguet F, Menguy I, Minoletti C, Nicolas MF, Pasquier O, Poirier B, Raux A, Riva L, Janiak P, Strobel H, Duclos O, Illiano S. Mallart S, et al. Among authors: orsatti l. J Med Chem. 2021 Feb 25;64(4):2139-2150. doi: 10.1021/acs.jmedchem.0c01533. Epub 2021 Feb 8. J Med Chem. 2021. PMID: 33555858
Turnover rate of coenzyme A in mouse brain and liver.
Orsatti L, Orsale MV, di Pasquale P, Vecchi A, Colaceci F, Ciammaichella A, Rossetti I, Bonelli F, Baumgaertel K, Liu K, Elbaum D, Monteagudo E. Orsatti L, et al. PLoS One. 2021 May 21;16(5):e0251981. doi: 10.1371/journal.pone.0251981. eCollection 2021. PLoS One. 2021. PMID: 34019583 Free PMC article.
Personalized Metabolic Profile by Synergic Use of NMR and HRMS.
Petrella G, Montesano C, Lentini S, Ciufolini G, Vanni D, Speziale R, Salonia A, Montorsi F, Summa V, Vago R, Orsatti L, Monteagudo E, Cicero DO. Petrella G, et al. Among authors: orsatti l. Molecules. 2021 Jul 8;26(14):4167. doi: 10.3390/molecules26144167. Molecules. 2021. PMID: 34299442 Free PMC article.
39 results