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R2R01: A long-acting single-chain peptide agonist of RXFP1 for renal and cardiovascular diseases.
Poirier B, Pasquier O, Chenede X, Corbier A, Prigent P, Azam A, Bernard C, Guillotel M, Gillot F, Riva L, Briand V, Ingenito R, Gauzy-Lazo L, Duclos O, Philippo C, Maillere B, Bianchi E, Mallart S, Janiak P, Illiano S. Poirier B, et al. Among authors: mallart s. Br J Pharmacol. 2024 Jul;181(13):1993-2011. doi: 10.1111/bph.16338. Epub 2024 Mar 7. Br J Pharmacol. 2024. PMID: 38450758
Design and synthesis of naturally-inspired SARS-CoV-2 inhibitors.
Hassan H, Chiavaralli J, Hassan A, Bedda L, Krischuns T, Chen KY, Li ASM, Delpal A, Decroly E, Vedadi M, Naffakh N, Agou F, Mallart S, Arafa RK, Arimondo PB. Hassan H, et al. Among authors: mallart s. RSC Med Chem. 2023 Jan 25;14(3):507-519. doi: 10.1039/d2md00149g. eCollection 2023 Mar 22. RSC Med Chem. 2023. PMID: 36970153 Free PMC article.
Fatty acid acylated peptide therapeutics: discovery of omega-n oxidation of the lipid chain as a novel metabolic pathway in preclinical species.
Esposito S, Krick A, Pasquier O, Bonche F, Ingenito R, Magotti P, Bianchi E, Monteagudo E, Gallo M, Cicero DO, Orsatti L, Veneziano M, Caretti F, Mele R, Roversi D, Gennari N, Brasseur D, Gauzy-Lazo L, Duclos O, Mauriac C, Illiano S, Mallart S. Esposito S, et al. Among authors: mallart s. J Pharm Biomed Anal. 2023 Apr 1;227:115256. doi: 10.1016/j.jpba.2023.115256. Epub 2023 Jan 18. J Pharm Biomed Anal. 2023. PMID: 36764268
Characterization of a new potent and long-lasting single chain peptide agonist of RXFP1 in cells and in vivo translational models.
Illiano S, Poirier B, Minoletti C, Pasquier O, Riva L, Chenede X, Menguy I, Guillotel M, Prigent P, Le Claire S, Gillot F, Thill G, Lo Presti F, Corbier A, Le Bail JC, Grailhe P, Monteagudo E, Ingenito R, Bianchi E, Philippo C, Duclos O, Mallart S, Bathgate R, Janiak P. Illiano S, et al. Among authors: mallart s. Sci Rep. 2022 Nov 28;12(1):20435. doi: 10.1038/s41598-022-24716-2. Sci Rep. 2022. PMID: 36443381 Free PMC article.
Potent Lys Patch-Containing Stapled Peptides Targeting PCSK9.
Bourbiaux K, Legrand B, Verdié P, Mallart S, Manette G, Minoletti C, Stepp JD, Prigent P, Le Bail JC, Gauzy-Lazo L, Duclos O, Martinez J, Amblard M. Bourbiaux K, et al. Among authors: mallart s. J Med Chem. 2021 Aug 12;64(15):10834-10848. doi: 10.1021/acs.jmedchem.0c02051. Epub 2021 Jul 15. J Med Chem. 2021. PMID: 34266235
Identification of Potent and Long-Acting Single-Chain Peptide Mimetics of Human Relaxin-2 for Cardiovascular Diseases.
Mallart S, Ingenito R, Bianchi E, Bresciani A, Esposito S, Gallo M, Magotti P, Monteagudo E, Orsatti L, Roversi D, Santoprete A, Tucci F, Veneziano M, Bartsch R, Boehm C, Brasseur D, Bruneau P, Corbier A, Froissant J, Gauzy-Lazo L, Gervat V, Marguet F, Menguy I, Minoletti C, Nicolas MF, Pasquier O, Poirier B, Raux A, Riva L, Janiak P, Strobel H, Duclos O, Illiano S. Mallart S, et al. J Med Chem. 2021 Feb 25;64(4):2139-2150. doi: 10.1021/acs.jmedchem.0c01533. Epub 2021 Feb 8. J Med Chem. 2021. PMID: 33555858