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Peptidase Activation by a Leader Peptide-Bound RiPP Recognition Element.
Kretsch AM, Gadgil MG, DiCaprio AJ, Barrett SE, Kille BL, Si Y, Zhu L, Mitchell DA. Kretsch AM, et al. Among authors: mitchell da. Biochemistry. 2023 Feb 21;62(4):956-967. doi: 10.1021/acs.biochem.2c00700. Epub 2023 Feb 3. Biochemistry. 2023. PMID: 36734655 Free PMC article.
Radical S-Adenosylmethionine Enzymes Involved in RiPP Biosynthesis.
Mahanta N, Hudson GA, Mitchell DA. Mahanta N, et al. Among authors: mitchell da. Biochemistry. 2017 Oct 10;56(40):5229-5244. doi: 10.1021/acs.biochem.7b00771. Epub 2017 Sep 22. Biochemistry. 2017. PMID: 28895719 Free PMC article. Review.
Bioinformatic Expansion and Discovery of Thiopeptide Antibiotics.
Schwalen CJ, Hudson GA, Kille B, Mitchell DA. Schwalen CJ, et al. Among authors: mitchell da. J Am Chem Soc. 2018 Aug 1;140(30):9494-9501. doi: 10.1021/jacs.8b03896. Epub 2018 Jul 20. J Am Chem Soc. 2018. PMID: 29983054 Free PMC article.
Bioinformatic Mapping of Radical S-Adenosylmethionine-Dependent Ribosomally Synthesized and Post-Translationally Modified Peptides Identifies New Cα, Cβ, and Cγ-Linked Thioether-Containing Peptides.
Hudson GA, Burkhart BJ, DiCaprio AJ, Schwalen CJ, Kille B, Pogorelov TV, Mitchell DA. Hudson GA, et al. Among authors: mitchell da. J Am Chem Soc. 2019 May 22;141(20):8228-8238. doi: 10.1021/jacs.9b01519. Epub 2019 May 13. J Am Chem Soc. 2019. PMID: 31059252 Free PMC article.
Functional elucidation of TfuA in peptide backbone thioamidation.
Liu A, Si Y, Dong SH, Mahanta N, Penkala HN, Nair SK, Mitchell DA. Liu A, et al. Among authors: mitchell da. Nat Chem Biol. 2021 May;17(5):585-592. doi: 10.1038/s41589-021-00771-0. Epub 2021 Mar 11. Nat Chem Biol. 2021. PMID: 33707784 Free PMC article.
587 results