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Fmo induction as a tool to screen for pro-longevity drugs.
Geroscience. 2024 May 24. doi: 10.1007/s11357-024-01207-y. Online ahead of print.
Geroscience. 2024.
PMID: 38787463
FMO rewires metabolism to promote longevity through tryptophan and one carbon metabolism in C. elegans.
Choi HS, Bhat A, Howington MB, Schaller ML, Cox RL, Huang S, Beydoun S, Miller HA, Tuckowski AM, Mecano J, Dean ES, Jensen L, Beard DA, Evans CR, Leiser SF.
Choi HS, et al. Among authors: howington mb.
Nat Commun. 2023 Feb 2;14(1):562. doi: 10.1038/s41467-023-36181-0.
Nat Commun. 2023.
PMID: 36732543
Free PMC article.
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Flavin-Containing Monooxygenases Are Conserved Regulators of Stress Resistance and Metabolism.
Huang S, Howington MB, Dobry CJ, Evans CR, Leiser SF.
Huang S, et al. Among authors: howington mb.
Front Cell Dev Biol. 2021 Feb 12;9:630188. doi: 10.3389/fcell.2021.630188. eCollection 2021.
Front Cell Dev Biol. 2021.
PMID: 33644069
Free PMC article.
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Computational tools for geroscience.
Kruempel JCP, Howington MB, Leiser SF.
Kruempel JCP, et al. Among authors: howington mb.
Transl Med Aging. 2019;3:132-143. doi: 10.1016/j.tma.2019.11.004. Epub 2019 Nov 14.
Transl Med Aging. 2019.
PMID: 33241167
Free PMC article.
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