Ang KK - Search Results

1

Venetoclax and dinaciclib elicit synergistic preclinical efficacy against hypodiploid acute lymphoblastic leukemia.

Pariury H, Fandel J, Bachl S, Ang KK, Markossian S, Wilson CG, Braun BS, Popescu B, Wohlfeil M, Beckman K, Xirenayi S, Roy RP, Olshen AB, Smith C, Arkin MR, Loh ML, Diaz-Flores E. Pariury H, et al. Among authors: ang kk. Haematologica. 2023 May 1;108(5):1272-1283. doi: 10.3324/haematol.2022.281443. Haematologica. 2023. PMID: 36700399 Free PMC article.

2

Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch.

Gallagher CM, Garri C, Cain EL, Ang KK, Wilson CG, Chen S, Hearn BR, Jaishankar P, Aranda-Diaz A, Arkin MR, Renslo AR, Walter P. Gallagher CM, et al. Among authors: ang kk. Elife. 2016 Jul 20;5:e11878. doi: 10.7554/eLife.11878. Elife. 2016. PMID: 27435960 Free PMC article.

3

A Whole-Genome RNA Interference Screen Reveals a Role for Spry2 in Insulin Transcription and the Unfolded Protein Response.

Pappalardo Z, Gambhir Chopra D, Hennings TG, Richards H, Choe J, Yang K, Baeyens L, Ang K, Chen S, Arkin M, German MS, McManus MT, Ku GM. Pappalardo Z, et al. Diabetes. 2017 Jun;66(6):1703-1712. doi: 10.2337/db16-0962. Epub 2017 Feb 28. Diabetes. 2017. PMID: 28246293 Free PMC article.

4

Small-Molecule Screening for Genetic Diseases.

Markossian S, Ang KK, Wilson CG, Arkin MR. Markossian S, et al. Among authors: ang kk. Annu Rev Genomics Hum Genet. 2018 Aug 31;19:263-288. doi: 10.1146/annurev-genom-083117-021452. Epub 2018 May 23. Annu Rev Genomics Hum Genet. 2018. PMID: 29799800 Review.

5

Functional Assessment of 2,177 U.S. and International Drugs Identifies the Quinoline Nitroxoline as a Potent Amoebicidal Agent against the Pathogen Balamuthia mandrillaris.

Laurie MT, White CV, Retallack H, Wu W, Moser MS, Sakanari JA, Ang K, Wilson C, Arkin MR, DeRisi JL. Laurie MT, et al. mBio. 2018 Oct 30;9(5):e02051-18. doi: 10.1128/mBio.02051-18. mBio. 2018. PMID: 30377287 Free PMC article.

6

Identification of Plasmodium dipeptidyl aminopeptidase allosteric inhibitors by high throughput screening.

Sanchez MI, de Vries LE, Lehmann C, Lee JT, Ang KK, Wilson C, Chen S, Arkin MR, Bogyo M, Deu E. Sanchez MI, et al. Among authors: ang kk. PLoS One. 2019 Dec 18;14(12):e0226270. doi: 10.1371/journal.pone.0226270. eCollection 2019. PLoS One. 2019. PMID: 31851699 Free PMC article.

7

Stress Resistance Screen in a Human Primary Cell Line Identifies Small Molecules That Affect Aging Pathways and Extend Caenorhabditis elegans' Lifespan.

Zhang P, Zhai Y, Cregg J, Ang KK, Arkin M, Kenyon C. Zhang P, et al. Among authors: ang kk. G3 (Bethesda). 2020 Feb 6;10(2):849-862. doi: 10.1534/g3.119.400618. G3 (Bethesda). 2020. PMID: 31879284 Free PMC article.

8

Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.

Mendiola AS, Ryu JK, Bardehle S, Meyer-Franke A, Ang KK, Wilson C, Baeten KM, Hanspers K, Merlini M, Thomas S, Petersen MA, Williams A, Thomas R, Rafalski VA, Meza-Acevedo R, Tognatta R, Yan Z, Pfaff SJ, Machado MR, Bedard C, Rios Coronado PE, Jiang X, Wang J, Pleiss MA, Green AJ, Zamvil SS, Pico AR, Bruneau BG, Arkin MR, Akassoglou K. Mendiola AS, et al. Among authors: ang kk. Nat Immunol. 2020 May;21(5):513-524. doi: 10.1038/s41590-020-0654-0. Epub 2020 Apr 13. Nat Immunol. 2020. PMID: 32284594 Free PMC article.

9

Author Correction: Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.

Mendiola AS, Ryu JK, Bardehle S, Meyer-Franke A, Ang KK, Wilson C, Baeten KM, Hanspers K, Merlini M, Thomas S, Petersen MA, Williams A, Thomas R, Rafalski VA, Meza-Acevedo R, Tognatta R, Yan Z, Pfaff SJ, Machado MR, Bedard C, Coronado PER, Jiang X, Wang J, Pleiss MA, Green AJ, Zamvil SS, Pico AR, Bruneau BG, Arkin MR, Akassoglou K. Mendiola AS, et al. Among authors: ang kk. Nat Immunol. 2020 Sep;21(9):1135. doi: 10.1038/s41590-020-0754-x. Nat Immunol. 2020. PMID: 32661365

10

Multiparametric High-Content Assays to Measure Cell Health and Oxidative Damage as a Model for Drug-Induced Liver Injury.

Pohan G, Espinosa JA, Chen S, Ang KK, Arkin MR, Markossian S. Pohan G, et al. Among authors: ang kk. Curr Protoc Chem Biol. 2020 Dec;12(4):e90. doi: 10.1002/cpch.90. Curr Protoc Chem Biol. 2020. PMID: 33315311 Free PMC article.

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