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Increased Physiological GDNF Levels Have No Effect on Dopamine Neuron Protection and Restoration in a Proteasome Inhibition Mouse Model of Parkinson's Disease.
Olfat S, Mätlik K, Kopra JJ, Garton DR, Iivanainen VH, Bhattacharya D, Jakobsson J, Piepponen TP, Andressoo JO. Olfat S, et al. Among authors: piepponen tp. eNeuro. 2023 Feb 8;10(2):ENEURO.0097-22.2023. doi: 10.1523/ENEURO.0097-22.2023. Print 2023 Feb. eNeuro. 2023. PMID: 36690469 Free PMC article.
Constitutive Ret signaling leads to long-lasting expression of amphetamine-induced place conditioning via elevation of mesolimbic dopamine.
Kopra J, Villarta-Aguilera M, Savolainen M, Weingerl S, Myöhänen TT, Rannanpää S, Salvatore MF, Andressoo JO, Piepponen TP. Kopra J, et al. Among authors: piepponen tp. Neuropharmacology. 2018 Jan;128:221-230. doi: 10.1016/j.neuropharm.2017.10.010. Epub 2017 Oct 13. Neuropharmacology. 2018. PMID: 29031851 Free PMC article.
Elevated endogenous GDNF induces altered dopamine signalling in mice and correlates with clinical severity in schizophrenia.
Mätlik K, Garton DR, Montaño-Rodríguez AR, Olfat S, Eren F, Casserly L, Damdimopoulos A, Panhelainen A, Porokuokka LL, Kopra JJ, Turconi G, Schweizer N, Bereczki E, Piehl F, Engberg G, Cervenka S, Piepponen TP, Zhang FP, Sipilä P, Jakobsson J, Sellgren CM, Erhardt S, Andressoo JO. Mätlik K, et al. Among authors: piepponen tp. Mol Psychiatry. 2022 Aug;27(8):3247-3261. doi: 10.1038/s41380-022-01554-2. Epub 2022 May 26. Mol Psychiatry. 2022. PMID: 35618883 Free PMC article.
GDNF is not required for catecholaminergic neuron survival in vivo.
Kopra J, Vilenius C, Grealish S, Härma MA, Varendi K, Lindholm J, Castrén E, Võikar V, Björklund A, Piepponen TP, Saarma M, Andressoo JO. Kopra J, et al. Among authors: piepponen tp. Nat Neurosci. 2015 Mar;18(3):319-22. doi: 10.1038/nn.3941. Nat Neurosci. 2015. PMID: 25710828 Free PMC article.
GDNF Overexpression from the Native Locus Reveals its Role in the Nigrostriatal Dopaminergic System Function.
Kumar A, Kopra J, Varendi K, Porokuokka LL, Panhelainen A, Kuure S, Marshall P, Karalija N, Härma MA, Vilenius C, Lilleväli K, Tekko T, Mijatovic J, Pulkkinen N, Jakobson M, Jakobson M, Ola R, Palm E, Lindahl M, Strömberg I, Võikar V, Piepponen TP, Saarma M, Andressoo JO. Kumar A, et al. Among authors: piepponen tp. PLoS Genet. 2015 Dec 17;11(12):e1005710. doi: 10.1371/journal.pgen.1005710. eCollection 2015 Dec. PLoS Genet. 2015. PMID: 26681446 Free PMC article.
Glial cell line-derived neurotrophic factor receptor Rearranged during transfection agonist supports dopamine neurons in Vitro and enhances dopamine release In Vivo.
Mahato AK, Kopra J, Renko JM, Visnapuu T, Korhonen I, Pulkkinen N, Bespalov MM, Domanskyi A, Ronken E, Piepponen TP, Voutilainen MH, Tuominen RK, Karelson M, Sidorova YA, Saarma M. Mahato AK, et al. Among authors: piepponen tp. Mov Disord. 2020 Feb;35(2):245-255. doi: 10.1002/mds.27943. Epub 2019 Dec 16. Mov Disord. 2020. PMID: 31840869 Free PMC article.
57 results