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Identification of Side Chain Oxidized Sterols as Novel Liver X Receptor Agonists with Therapeutic Potential in the Treatment of Cardiovascular and Neurodegenerative Diseases.
Zhan N, Wang B, Martens N, Liu Y, Zhao S, Voortman G, van Rooij J, Leijten F, Vanmierlo T, Kuipers F, Jonker JW, Bloks VW, Lütjohann D, Palumbo M, Zimetti F, Adorni MP, Liu H, Mulder MT. Zhan N, et al. Int J Mol Sci. 2023 Jan 9;24(2):1290. doi: 10.3390/ijms24021290. Int J Mol Sci. 2023. PMID: 36674804 Free PMC article.
24(S)-Saringosterol Prevents Cognitive Decline in a Mouse Model for Alzheimer's Disease.
Martens N, Schepers M, Zhan N, Leijten F, Voortman G, Tiane A, Rombaut B, Poisquet J, Sande NV, Kerksiek A, Kuipers F, Jonker JW, Liu H, Lütjohann D, Vanmierlo T, Mulder MT. Martens N, et al. Among authors: zhan n. Mar Drugs. 2021 Mar 27;19(4):190. doi: 10.3390/md19040190. Mar Drugs. 2021. PMID: 33801706 Free PMC article.
24(R, S)-Saringosterol - From artefact to a biological medical agent.
Vanbrabant K, Van Meel D, Kerksiek A, Friedrichs S, Dubbeldam M, Schepers M, Zhan N, Gutbrod K, Dörmann P, Liu HB, Mulder MT, Vanmierlo T, Lütjohann D. Vanbrabant K, et al. Among authors: zhan n. J Steroid Biochem Mol Biol. 2021 Sep;212:105942. doi: 10.1016/j.jsbmb.2021.105942. Epub 2021 Jun 16. J Steroid Biochem Mol Biol. 2021. PMID: 34144153
Activation of Liver X Receptors and Peroxisome Proliferator-Activated Receptors by Lipid Extracts of Brown Seaweeds: A Potential Application in Alzheimer's Disease?
Martens N, Zhan N, Voortman G, Leijten FPJ, van Rheenen C, van Leerdam S, Geng X, Huybrechts M, Liu H, Jonker JW, Kuipers F, Lütjohann D, Vanmierlo T, Mulder MT. Martens N, et al. Among authors: zhan n. Nutrients. 2023 Jun 30;15(13):3004. doi: 10.3390/nu15133004. Nutrients. 2023. PMID: 37447330 Free PMC article.
187 results