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Identification of Side Chain Oxidized Sterols as Novel Liver X Receptor Agonists with Therapeutic Potential in the Treatment of Cardiovascular and Neurodegenerative Diseases.
Zhan N, Wang B, Martens N, Liu Y, Zhao S, Voortman G, van Rooij J, Leijten F, Vanmierlo T, Kuipers F, Jonker JW, Bloks VW, Lütjohann D, Palumbo M, Zimetti F, Adorni MP, Liu H, Mulder MT. Zhan N, et al. Among authors: leijten f. Int J Mol Sci. 2023 Jan 9;24(2):1290. doi: 10.3390/ijms24021290. Int J Mol Sci. 2023. PMID: 36674804 Free PMC article.
Pleiotropic Effect of Human ApoE4 on Cerebral Ceramide and Saturated Fatty Acid Levels.
den Hoedt S, Janssen CIF, Astarita G, Piomelli D, Leijten FPJ, Crivelli SM, Verhoeven AJM, de Vries HE, Walter J, Martinez-Martinez P, Sijbrands EJG, Kiliaan AJ, Mulder MT. den Hoedt S, et al. Among authors: leijten fpj. J Alzheimers Dis. 2017;60(3):769-781. doi: 10.3233/JAD-160739. J Alzheimers Dis. 2017. PMID: 28035926
Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer's disease mouse model.
Bogie J, Hoeks C, Schepers M, Tiane A, Cuypers A, Leijten F, Chintapakorn Y, Suttiyut T, Pornpakakul S, Struik D, Kerksiek A, Liu HB, Hellings N, Martinez-Martinez P, Jonker JW, Dewachter I, Sijbrands E, Walter J, Hendriks J, Groen A, Staels B, Lütjohann D, Vanmierlo T, Mulder M. Bogie J, et al. Among authors: leijten f. Sci Rep. 2019 Mar 20;9(1):4908. doi: 10.1038/s41598-019-41399-4. Sci Rep. 2019. PMID: 30894635 Free PMC article.
How significant is the antifibrinolytic effect of lipoprotein(a) for blood clot lysis?
Rijken DC, de Vries JJ, Malfliet JJMC, Bos S, Kronenberg F, Leijten FP, Roeters van Lennep JE, Uitte de Willige S, van der Zee L, Mulder MT. Rijken DC, et al. Among authors: leijten fp. Thromb Res. 2021 Feb;198:210-212. doi: 10.1016/j.thromres.2020.12.014. Epub 2020 Dec 26. Thromb Res. 2021. PMID: 33373926 No abstract available.
24(S)-Saringosterol Prevents Cognitive Decline in a Mouse Model for Alzheimer's Disease.
Martens N, Schepers M, Zhan N, Leijten F, Voortman G, Tiane A, Rombaut B, Poisquet J, Sande NV, Kerksiek A, Kuipers F, Jonker JW, Liu H, Lütjohann D, Vanmierlo T, Mulder MT. Martens N, et al. Among authors: leijten f. Mar Drugs. 2021 Mar 27;19(4):190. doi: 10.3390/md19040190. Mar Drugs. 2021. PMID: 33801706 Free PMC article.
Effects of Sex, Age, and Apolipoprotein E Genotype on Brain Ceramides and Sphingosine-1-Phosphate in Alzheimer's Disease and Control Mice.
den Hoedt S, Crivelli SM, Leijten FPJ, Losen M, Stevens JAA, Mané-Damas M, de Vries HE, Walter J, Mirzaian M, Sijbrands EJG, Aerts JMFG, Verhoeven AJM, Martinez-Martinez P, Mulder MT. den Hoedt S, et al. Among authors: leijten fpj. Front Aging Neurosci. 2021 Oct 27;13:765252. doi: 10.3389/fnagi.2021.765252. eCollection 2021. Front Aging Neurosci. 2021. PMID: 34776936 Free PMC article.
Breakfast partly restores the anti-inflammatory function of high-density lipoproteins from patients with type 2 diabetes mellitus.
Lemmers RFH, Martens NEMA, Maas AH, van Vark-van der Zee LC, Leijten FPJ, Groot-van Ruijven CM, van Hoek M, Lieverse AG, Sijbrands EJG, Haak HR, Leenen PJM, Verhoeven AJM, Dik WA, Mulder MT. Lemmers RFH, et al. Among authors: leijten fpj. Atheroscler Plus. 2021 Aug 24;44:43-50. doi: 10.1016/j.athplu.2021.08.006. eCollection 2021 Oct. Atheroscler Plus. 2021. PMID: 36644668 Free PMC article.
Activation of Liver X Receptors and Peroxisome Proliferator-Activated Receptors by Lipid Extracts of Brown Seaweeds: A Potential Application in Alzheimer's Disease?
Martens N, Zhan N, Voortman G, Leijten FPJ, van Rheenen C, van Leerdam S, Geng X, Huybrechts M, Liu H, Jonker JW, Kuipers F, Lütjohann D, Vanmierlo T, Mulder MT. Martens N, et al. Among authors: leijten fpj. Nutrients. 2023 Jun 30;15(13):3004. doi: 10.3390/nu15133004. Nutrients. 2023. PMID: 37447330 Free PMC article.
Effect of diet-induced weight loss on lipoprotein(a) levels in obese individuals with and without type 2 diabetes.
Berk KA, Yahya R, Verhoeven AJM, Touw J, Leijten FP, van Rossum EF, Wester VL, Lips MA, Pijl H, Timman R, Erhart G, Kronenberg F, Roeters van Lennep JE, Sijbrands EJG, Mulder MT. Berk KA, et al. Among authors: leijten fp. Diabetologia. 2017 Jun;60(6):989-997. doi: 10.1007/s00125-017-4246-y. Epub 2017 Apr 6. Diabetologia. 2017. PMID: 28386638 Free PMC article.
Altered Functionality of Lipoprotein(a) Impacts on Angiogenesis in Diabetic Retinopathy.
Shariatzadeh M, Nagtzaam NMA, van Vark-van der Zee L, van Holten-Neelen C, Verhoeven AJM, Dehairs J, Swinnen JV, Leijten F, Ten Berge JC, Ciriano JPM, Wong KT, Mulder M, Leenen PJM, Dik WA. Shariatzadeh M, et al. Among authors: leijten f. Invest Ophthalmol Vis Sci. 2023 May 1;64(5):8. doi: 10.1167/iovs.64.5.8. Invest Ophthalmol Vis Sci. 2023. PMID: 37159194 Free PMC article.
234 results