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Protective Effects of Therapeutic Neutrophil Depletion and Myeloperoxidase Inhibition on Left Ventricular Function and Remodeling in Myocardial Infarction.
Guthoff H, Hof A, Klinke A, Maaß M, Konradi J, Mehrkens D, Geißen S, Nettersheim FS, Braumann S, Michaelsson E, Nies RJ, Lee S, Redzinski MC, Peters VBM, Nemade HN, von Stein P, Winkels H, Rudolph V, Baldus S, Adam M, Mollenhauer M. Guthoff H, et al. Among authors: rudolph v. Antioxidants (Basel). 2022 Dec 24;12(1):33. doi: 10.3390/antiox12010033. Antioxidants (Basel). 2022. PMID: 36670895 Free PMC article.
Myeloperoxidase mediates neutrophil activation by association with CD11b/CD18 integrins.
Lau D, Mollnau H, Eiserich JP, Freeman BA, Daiber A, Gehling UM, Brümmer J, Rudolph V, Münzel T, Heitzer T, Meinertz T, Baldus S. Lau D, et al. Among authors: rudolph v. Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):431-6. doi: 10.1073/pnas.0405193102. Epub 2004 Dec 29. Proc Natl Acad Sci U S A. 2005. PMID: 15625114 Free PMC article.
Heparins increase endothelial nitric oxide bioavailability by liberating vessel-immobilized myeloperoxidase.
Baldus S, Rudolph V, Roiss M, Ito WD, Rudolph TK, Eiserich JP, Sydow K, Lau D, Szöcs K, Klinke A, Kubala L, Berglund L, Schrepfer S, Deuse T, Haddad M, Risius T, Klemm H, Reichenspurner HC, Meinertz T, Heitzer T. Baldus S, et al. Among authors: rudolph tk, rudolph v. Circulation. 2006 Apr 18;113(15):1871-8. doi: 10.1161/CIRCULATIONAHA.105.590083. Epub 2006 Apr 10. Circulation. 2006. PMID: 16606792
Activation of polymorphonuclear neutrophils in patients with impaired left ventricular function.
Rudolph V, Rudolph TK, Hennings JC, Blankenberg S, Schnabel R, Steven D, Haddad M, Knittel K, Wende S, Wenzel J, Münzel T, Heitzer T, Meinertz T, Hübner C, Baldus S. Rudolph V, et al. Among authors: rudolph tk. Free Radic Biol Med. 2007 Oct 15;43(8):1189-96. doi: 10.1016/j.freeradbiomed.2007.07.016. Epub 2007 Jul 19. Free Radic Biol Med. 2007. PMID: 17854714
Bivalirudin decreases NO bioavailability by vascular immobilization of myeloperoxidase.
Rudolph V, Rudolph TK, Schopfer FJ, Bonacci G, Lau D, Szöcs K, Klinke A, Meinertz T, Freeman BA, Baldus S. Rudolph V, et al. Among authors: rudolph tk. J Pharmacol Exp Ther. 2008 Nov;327(2):324-31. doi: 10.1124/jpet.108.142414. Epub 2008 Aug 13. J Pharmacol Exp Ther. 2008. PMID: 18701766 Free PMC article. Clinical Trial.
241 results