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Thorectidiol A Isolated from the Marine Sponge Dactylospongia elegans Disrupts Interactions of the SARS-CoV-2 Spike Receptor Binding Domain with the Host ACE2 Receptor.
Williams DE, Cassel J, Zhu JL, Yang JX, de Voogd NJ, Matainaho T, Salvino JM, Wang YA, Montaner LJ, Tietjen I, Andersen RJ. Williams DE, et al. Among authors: cassel j. J Nat Prod. 2023 Mar 24;86(3):582-588. doi: 10.1021/acs.jnatprod.2c01030. Epub 2023 Jan 19. J Nat Prod. 2023. PMID: 36657039
Dysregulated expression of cholesterol biosynthetic genes in Alzheimer's disease alters epigenomic signatures of hippocampal neurons.
Paiva I, Seguin J, Grgurina I, Singh AK, Cosquer B, Plassard D, Tzeplaeff L, Le Gras S, Cotellessa L, Decraene C, Gambi J, Alcala-Vida R, Eswaramoorthy M, Buée L, Cassel JC, Giacobini P, Blum D, Merienne K, Kundu TK, Boutillier AL. Paiva I, et al. Among authors: cassel jc. Neurobiol Dis. 2024 May 22:106538. doi: 10.1016/j.nbd.2024.106538. Online ahead of print. Neurobiol Dis. 2024. PMID: 38789057
Metabolomic Analysis and Antiviral Screening of a Marine Algae Library Yield Jobosic Acid (2,5-Dimethyltetradecanoic Acid) as a Selective Inhibitor of SARS-CoV-2.
Matos-Hernández ML, Samples R, Dyer G, Casimir Montán VM, Morales-Colón CA, Salvino JM, Montaner LJ, Cassel JA, Messick TE, Tietjen I, Caro-Diaz EJE. Matos-Hernández ML, et al. Among authors: cassel ja. J Nat Prod. 2024 May 23. doi: 10.1021/acs.jnatprod.3c01071. Online ahead of print. J Nat Prod. 2024. PMID: 38781491
5-chloro-3-(2-(2,4-dinitrophenyl) hydrazono)indolin-2-one: synthesis, characterization, biochemical and computational screening against SARS-CoV-2.
Majoumo-Mbe F, Sangbong NA, Tadjong Tcho A, Namba-Nzanguim CT, Simoben CV, Eni DB, Alhaji Isa M, Poli ANR, Cassel J, Salvino JM, Montaner LJ, Tietjen I, Ntie-Kang F. Majoumo-Mbe F, et al. Among authors: cassel j. Chem Zvesti. 2024;78(6):3431-3441. doi: 10.1007/s11696-023-03274-5. Epub 2024 Mar 14. Chem Zvesti. 2024. PMID: 38685970 Free PMC article.
451 results