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A hepatitis B virus core antigen-based virus-like particle vaccine expressing SARS-CoV-2 B and T cell epitopes induces epitope-specific humoral and cell-mediated immune responses but confers limited protection against SARS-CoV-2 infection.
Hassebroek AM, Sooryanarain H, Heffron CL, Hawks SA, LeRoith T, Cecere TE, Stone WB, Walter D, Mahsoub HM, Wang B, Tian D, Ivester HM, Allen IC, Auguste AJ, Duggal NK, Zhang C, Meng XJ. Hassebroek AM, et al. Among authors: stone wb. J Med Virol. 2023 Feb;95(2):e28503. doi: 10.1002/jmv.28503. J Med Virol. 2023. PMID: 36655751 Free PMC article.
Novel murine models for studying Cache Valley virus pathogenesis and in utero transmission.
López K, Wilson SN, Coutermash-Ott S, Tanelus M, Stone WB, Porier DL, Auguste DI, Muller JA, Allicock OM, Paulson SL, Erasmus JH, Auguste AJ. López K, et al. Among authors: stone wb. Emerg Microbes Infect. 2021 Dec;10(1):1649-1659. doi: 10.1080/22221751.2021.1965497. Emerg Microbes Infect. 2021. PMID: 34353229 Free PMC article.
A Novel Bacterial Protease Inhibitor Adjuvant in RBD-Based COVID-19 Vaccine Formulations Containing Alum Increases Neutralizing Antibodies, Specific Germinal Center B Cells and Confers Protection Against SARS-CoV-2 Infection in Mice.
Coria LM, Saposnik LM, Pueblas Castro C, Castro EF, Bruno LA, Stone WB, Pérez PS, Darriba ML, Chemes LB, Alcain J, Mazzitelli I, Varese A, Salvatori M, Auguste AJ, Álvarez DE, Pasquevich KA, Cassataro J. Coria LM, et al. Among authors: stone wb. Front Immunol. 2022 Feb 28;13:844837. doi: 10.3389/fimmu.2022.844837. eCollection 2022. Front Immunol. 2022. PMID: 35296091 Free PMC article.
Nanobodies against SARS-CoV-2 reduced virus load in the brain of challenged mice and neutralized Wuhan, Delta and Omicron Variants.
Pavan MF, Bok M, Juan RBS, Malito JP, Marcoppido GA, Franco DR, Militello DA, Schammas JM, Bari S; Argentinian AntiCovid Consortium; Stone WB, López K, Porier DL, Muller J, Auguste AJ, Yuan L, Wigdorovitz A, Parreño V, Ibañez LI. Pavan MF, et al. Among authors: stone wb. bioRxiv [Preprint]. 2023 Mar 14:2023.03.14.532528. doi: 10.1101/2023.03.14.532528. bioRxiv. 2023. PMID: 36993215 Free PMC article. Preprint.
A Gamma-adapted subunit vaccine induces broadly neutralizing antibodies against SARS-CoV-2 variants and protects mice from infection.
Coria LM, Rodriguez JM, Demaria A, Bruno LA, Medrano MR, Castro CP, Castro EF, Del Priore SA, Hernando Insua AC, Kaufmann IG, Saposnik LM, Stone WB, Prado L, Notaro US, Amweg AN, Diaz PU, Avaro M, Ortega H, Ceballos A, Krum V, Zurvarra FM, Sidabra JE, Drehe I, Baqué JA, Li Causi M, De Nichilo AV, Payes CJ, Southard T, Vega JC, Auguste AJ, Álvarez DE, Flo JM, Pasquevich KA, Cassataro J. Coria LM, et al. Among authors: stone wb. Nat Commun. 2024 Feb 2;15(1):997. doi: 10.1038/s41467-024-45180-8. Nat Commun. 2024. PMID: 38307851 Free PMC article.
SARS-CoV-2 Specific Nanobodies Neutralize Different Variants of Concern and Reduce Virus Load in the Brain of h-ACE2 Transgenic Mice.
Pavan MF, Bok M, Betanzos San Juan R, Malito JP, Marcoppido GA, Franco DR, Militelo DA, Schammas JM, Bari SE, Stone W, López K, Porier DL, Muller JA, Auguste AJ, Yuan L, Wigdorovitz A, Parreño VG, Ibañez LI. Pavan MF, et al. Viruses. 2024 Jan 25;16(2):185. doi: 10.3390/v16020185. Viruses. 2024. PMID: 38399961 Free PMC article.
Curcumin Reduces Amyloid Beta Oligomer Interactions with Anionic Membranes.
Sallaberry CA, Voss BJ, Stone WB, Estrada F, Bhatia A, Soto JD, Griffin CW, Vander Zanden CM. Sallaberry CA, et al. Among authors: stone wb. ACS Chem Neurosci. 2023 Nov 15;14(22):4026-4038. doi: 10.1021/acschemneuro.3c00512. Epub 2023 Oct 31. ACS Chem Neurosci. 2023. PMID: 37906715
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