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Identification and Characterization of ML321: A Novel and Highly Selective D2 Dopamine Receptor Antagonist with Efficacy in Animal Models That Predict Atypical Antipsychotic Activity.
Free RB, Nilson AN, Boldizsar NM, Doyle TB, Rodriguiz RM, Pogorelov VM, Machino M, Lee KH, Bertz JW, Xu J, Lim HD, Dulcey AE, Mach RH, Woods JH, Lane JR, Shi L, Marugan JJ, Wetsel WC, Sibley DR. Free RB, et al. Among authors: dulcey ae. ACS Pharmacol Transl Sci. 2022 Dec 30;6(1):151-170. doi: 10.1021/acsptsci.2c00202. eCollection 2023 Jan 13. ACS Pharmacol Transl Sci. 2022. PMID: 36654757 Free PMC article.
Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice.
Chandía-Cristi A, Gutiérrez DA, Dulcey AE, Lara M, Vargas L, Lin YH, Jimenez-Muñoz P, Larenas G, Xu X, Wang A, Owens A, Dextras C, Chen Y, Pinto C, Marín T, Almarza-Salazar H, Acevedo K, Cancino GI, Hu X, Rojas P, Ferrer M, Southall N, Henderson MJ, Zanlungo S, Marugan JJ, Álvarez R A. Chandía-Cristi A, et al. Among authors: dulcey ae. Cell Rep. 2024 Apr 23;43(5):114144. doi: 10.1016/j.celrep.2024.114144. Online ahead of print. Cell Rep. 2024. PMID: 38656874 Free article.
c-Abl tyrosine kinase down-regulation as target for memory improvement in Alzheimer's disease.
León R, Gutiérrez DA, Pinto C, Morales C, de la Fuente C, Riquelme C, Cortés BI, González-Martin A, Chamorro D, Espinosa N, Fuentealba P, Cancino GI, Zanlungo S, Dulcey AE, Marugan JJ, Álvarez Rojas A. León R, et al. Among authors: dulcey ae. Front Aging Neurosci. 2023 Jun 5;15:1180987. doi: 10.3389/fnagi.2023.1180987. eCollection 2023. Front Aging Neurosci. 2023. PMID: 37358955 Free PMC article.
c-Abl Phosphorylates MFN2 to Regulate Mitochondrial Morphology in Cells under Endoplasmic Reticulum and Oxidative Stress, Impacting Cell Survival and Neurodegeneration.
Martinez A, Lamaizon CM, Valls C, Llambi F, Leal N, Fitzgerald P, Guy C, Kamiński MM, Inestrosa NC, van Zundert B, Cancino GI, Dulcey AE, Zanlungo S, Marugan JJ, Hetz C, Green DR, Alvarez AR. Martinez A, et al. Among authors: dulcey ae. Antioxidants (Basel). 2023 Nov 16;12(11):2007. doi: 10.3390/antiox12112007. Antioxidants (Basel). 2023. PMID: 38001860 Free PMC article.
c-Abl Activation Linked to Autophagy-Lysosomal Dysfunction Contributes to Neurological Impairment in Niemann-Pick Type A Disease.
Marín T, Dulcey AE, Campos F, de la Fuente C, Acuña M, Castro J, Pinto C, Yañez MJ, Cortez C, McGrath DW, Sáez PJ, Gorshkov K, Zheng W, Southall N, Carmo-Fonseca M, Marugán J, Alvarez AR, Zanlungo S. Marín T, et al. Among authors: dulcey ae. Front Cell Dev Biol. 2022 Mar 18;10:844297. doi: 10.3389/fcell.2022.844297. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35399514 Free PMC article.
Fluoxazolevir inhibits hepatitis C virus infection in humanized chimeric mice by blocking viral membrane fusion.
Ma CD, Imamura M, Talley DC, Rolt A, Xu X, Wang AQ, Le D, Uchida T, Osawa M, Teraoka Y, Li K, Hu X, Park SB, Chalasani N, Irvin PH, Dulcey AE, Southall N, Marugan JJ, Hu Z, Chayama K, Frankowski KJ, Liang TJ. Ma CD, et al. Among authors: dulcey ae. Nat Microbiol. 2020 Dec;5(12):1532-1541. doi: 10.1038/s41564-020-0781-2. Epub 2020 Aug 31. Nat Microbiol. 2020. PMID: 32868923 Free PMC article.
Correction: Inhibition of glutathione peroxidase mediates the collateral sensitivity of multidrug-resistant cells to tiopronin.
Hall MD, Marshall TS, Kwit ADT, Miller Jenkins LM, Dulcey AE, Madigan JP, Pluchino KM, Goldsborough AS, Brimacombe KR, Griffiths GL, Gottesman MM. Hall MD, et al. Among authors: dulcey ae. J Biol Chem. 2020 Mar 27;295(13):4370. doi: 10.1074/jbc.AAC120.013256. J Biol Chem. 2020. PMID: 32221035 Free PMC article. No abstract available.
38 results