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RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells.
Chen F, Gurler SB, Novo D, Selli C, Alferez DG, Eroglu S, Pavlou K, Zhang J, Sims AH, Humphreys NE, Adamson A, Campbell A, Sansom OJ, Tournier C, Clarke RB, Brennan K, Streuli CH, Ucar A. Chen F, et al. Among authors: sansom oj. Oncogene. 2023 Feb;42(9):679-692. doi: 10.1038/s41388-022-02574-6. Epub 2023 Jan 5. Oncogene. 2023. PMID: 36599922 Free PMC article.
GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine.
Ferro R, Adamska A, Lattanzio R, Mavrommati I, Edling CE, Arifin SA, Fyffe CA, Sala G, Sacchetto L, Chiorino G, De Laurenzi V, Piantelli M, Sansom OJ, Maffucci T, Falasca M. Ferro R, et al. Among authors: sansom oj. Oncogene. 2018 Dec;37(49):6368-6382. doi: 10.1038/s41388-018-0390-1. Epub 2018 Jul 30. Oncogene. 2018. PMID: 30061636
CRISPR activation screen in mice identifies novel membrane proteins enhancing pulmonary metastatic colonisation.
van der Weyden L, Harle V, Turner G, Offord V, Iyer V, Droop A, Swiatkowska A, Rabbie R, Campbell AD, Sansom OJ, Pardo M, Choudhary JS, Ferreira I, Tullett M, Arends MJ, Speak AO, Adams DJ. van der Weyden L, et al. Among authors: sansom oj. Commun Biol. 2021 Mar 23;4(1):395. doi: 10.1038/s42003-021-01912-w. Commun Biol. 2021. PMID: 33758365 Free PMC article.
355 results