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Modulating glycosphingolipid metabolism and autophagy improves outcomes in pre-clinical models of myeloma bone disease.
Leng H, Zhang H, Li L, Zhang S, Wang Y, Chavda SJ, Galas-Filipowicz D, Lou H, Ersek A, Morris EV, Sezgin E, Lee YH, Li Y, Lechuga-Vieco AV, Tian M, Mi JQ, Yong K, Zhong Q, Edwards CM, Simon AK, Horwood NJ. Leng H, et al. Among authors: simon ak. Nat Commun. 2022 Dec 22;13(1):7868. doi: 10.1038/s41467-022-35358-3. Nat Commun. 2022. PMID: 36550101 Free PMC article.
Autophagy and Immune Senescence.
Zhang H, Puleston DJ, Simon AK. Zhang H, et al. Among authors: simon ak. Trends Mol Med. 2016 Aug;22(8):671-686. doi: 10.1016/j.molmed.2016.06.001. Epub 2016 Jul 7. Trends Mol Med. 2016. PMID: 27395769 Review.
Adipocyte autophagy limits gut inflammation by controlling oxylipin and IL-10.
Richter FC, Friedrich M, Kampschulte N, Piletic K, Alsaleh G, Zummach R, Hecker J, Pohin M, Ilott N, Guschina I, Wideman SK, Johnson E, Borsa M, Hahn P, Morriseau C, Hammock BD, Schipper HS, Edwards CM, Zechner R, Siegmund B, Weidinger C, Schebb NH, Powrie F, Simon AK. Richter FC, et al. Among authors: simon ak. EMBO J. 2023 Mar 15;42(6):e112202. doi: 10.15252/embj.2022112202. Epub 2023 Feb 16. EMBO J. 2023. PMID: 36795015 Free PMC article.
Proteostasis in T cell aging.
Gressler AE, Leng H, Zinecker H, Simon AK. Gressler AE, et al. Among authors: simon ak. Semin Immunol. 2023 Nov;70:101838. doi: 10.1016/j.smim.2023.101838. Epub 2023 Sep 12. Semin Immunol. 2023. PMID: 37708826 Free PMC article. Review.
The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance.
Mortensen M, Soilleux EJ, Djordjevic G, Tripp R, Lutteropp M, Sadighi-Akha E, Stranks AJ, Glanville J, Knight S, Jacobsen SE, Kranc KR, Simon AK. Mortensen M, et al. Among authors: simon ak. J Exp Med. 2011 Mar 14;208(3):455-67. doi: 10.1084/jem.20101145. Epub 2011 Feb 21. J Exp Med. 2011. PMID: 21339326 Free PMC article.
117 results