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Page 1
Selective NR1/2B N-methyl-D-aspartate receptor antagonists among indole-2-carboxamides and benzimidazole-2-carboxamides.
Borza I, Bozó E, Barta-Szalai G, Kiss C, Tárkányi G, Demeter A, Gáti T, Háda V, Kolok S, Gere A, Fodor L, Nagy J, Galgóczy K, Magdó I, Agai B, Fetter J, Bertha F, Keserü GM, Horváth C, Farkas S, Greiner I, Domány G. Borza I, et al. Among authors: magdo i. J Med Chem. 2007 Mar 8;50(5):901-14. doi: 10.1021/jm060420k. Epub 2007 Feb 10. J Med Chem. 2007. PMID: 17290978
Novel sulfonamides having dual dopamine D2 and D3 receptor affinity show in vivo antipsychotic efficacy with beneficial cognitive and EPS profile.
Agai-Csongor E, Nógrádi K, Galambos J, Vágó I, Bielik A, Magdó I, Ignácz-Szendrei G, Keseru GM, Greiner I, Laszlovszky I, Schmidt E, Kiss B, Sághy K, Laszy J, Gyertyán I, Zájer-Balázs M, Gémesi L, Domány G. Agai-Csongor E, et al. Among authors: magdo i. Bioorg Med Chem Lett. 2007 Oct 1;17(19):5340-4. doi: 10.1016/j.bmcl.2007.08.015. Epub 2007 Aug 15. Bioorg Med Chem Lett. 2007. PMID: 17720494
Thieno[2,3-b]pyridines as negative allosteric modulators of metabotropic GluR5 receptors: hit-to-lead optimization.
Nógrádi K, Wágner G, Domány G, Bobok A, Magdó I, Kiss B, Kolok S, Fónagy K, Gyertyán I, Háda V, Kóti J, Gál K, Farkas S, Keserű GM, Greiner I, Szombathelyi Z. Nógrádi K, et al. Among authors: magdo i. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3845-9. doi: 10.1016/j.bmcl.2014.06.057. Epub 2014 Jun 27. Bioorg Med Chem Lett. 2014. PMID: 25017030
Thieno[2,3-b]pyridines as negative allosteric modulators of metabotropic GluR5 receptors: Lead optimization.
Nógrádi K, Wágner G, Domány G, Bobok A, Magdó I, Kolok S, Mikó-Bakk ML, Vastag M, Sághy K, Gyertyán I, Kóti J, Gál K, Farkas S, Keserű GM, Greiner I, Szombathelyi Z. Nógrádi K, et al. Among authors: magdo i. Bioorg Med Chem Lett. 2015 Apr 15;25(8):1724-1729. doi: 10.1016/j.bmcl.2015.02.073. Epub 2015 Mar 7. Bioorg Med Chem Lett. 2015. PMID: 25791451
Discovery of New Heterocyclic Ring Systems as Novel and Potent V1A Receptor Antagonists.
Baska F, Szántó G, Bozó É, Szakács Z, Dékány M, Szondiné Kordás K, Domány-Kovács K, Kurkó D, Hodoscsek B, Magdó I, Krámos B, Béni Z, Vastag M, Bata I. Baska F, et al. Among authors: magdo i. ACS Chem Neurosci. 2020 Nov 4;11(21):3532-3540. doi: 10.1021/acschemneuro.0c00486. Epub 2020 Oct 21. ACS Chem Neurosci. 2020. PMID: 33084311
Synthesis and Characterization of New V1A Antagonist Compounds: The Separation of Four Atropisomeric Stereoisomers.
Szeleczky Z, Szakács Z, Bozó É, Baska F, Vukics K, Lévai S, Temesvári K, Vass E, Béni Z, Krámos B, Magdó I, Szántay C Jr, Kóti J, Domány-Kovács K, Greiner I, Bata I. Szeleczky Z, et al. Among authors: magdo i. J Med Chem. 2021 Jul 22;64(14):10445-10468. doi: 10.1021/acs.jmedchem.1c00863. Epub 2021 Jul 13. J Med Chem. 2021. PMID: 34255509
Novel-Type GABAB PAMs: Structure-Activity Relationship in Light of the Protein Structure.
Krámos B, Hadady Z, Makó A, Szántó G, Felföldi N, Magdó I, Bobok AÁ, Bata I, Román V, Visegrády A, Keserű GM, Greiner I, Éles J. Krámos B, et al. Among authors: magdo i. ACS Med Chem Lett. 2024 Mar 1;15(3):396-405. doi: 10.1021/acsmedchemlett.3c00560. eCollection 2024 Mar 14. ACS Med Chem Lett. 2024. PMID: 38505850