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FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty.
Platt JR, Todd OM, Hall P, Craig Z, Quyn A, Seymour M, Braun M, Roodhart J, Punt C, Christou N, Taieb J, Karoui M, Brown J, Cairns DA, Morton D, Gilbert A, Seligmann JF. Platt JR, et al. Among authors: roodhart j. ESMO Open. 2023 Feb;8(1):100642. doi: 10.1016/j.esmoop.2022.100642. Epub 2022 Dec 20. ESMO Open. 2023. PMID: 36549127 Free PMC article. Review.
A review of the sensitivity of metastatic colorectal cancer patients with deficient mismatch repair to standard-of-care chemotherapy and monoclonal antibodies, with recommendations for future research.
Wensink E, Bond M, Kucukkose E, May A, Vink G, Koopman M, Kranenburg O, Roodhart J. Wensink E, et al. Among authors: roodhart j. Cancer Treat Rev. 2021 Apr;95:102174. doi: 10.1016/j.ctrv.2021.102174. Epub 2021 Mar 1. Cancer Treat Rev. 2021. PMID: 33721596 Free article. Review.
Trends in Use and Perceptions About Triplet Chemotherapy Plus Bevacizumab for Metastatic Colorectal Cancer.
van Nassau SC, Bond MJ, Scheerman I, van Breeschoten J, Kessels R, Valkenburg-van Iersel LB, Verheul HM, Buffart TE, Mekenkamp LJ, Lemmens VE, Koopman M, Bol GM; EXCITE (From Clinical Trial to Bedside: Triplet Chemotherapy in Metastatic Colorectal Cancer) Study Group. van Nassau SC, et al. JAMA Netw Open. 2021 Sep 1;4(9):e2124766. doi: 10.1001/jamanetworkopen.2021.24766. JAMA Netw Open. 2021. PMID: 34505885 Free PMC article.
DNA damage induces p53-independent apoptosis through ribosome stalling.
Boon NJ, Oliveira RA, Körner PR, Kochavi A, Mertens S, Malka Y, Voogd R, van der Horst SEM, Huismans MA, Smabers LP, Draper JM, Wessels LFA, Haahr P, Roodhart JML, Schumacher TNM, Snippert HJ, Agami R, Brummelkamp TR. Boon NJ, et al. Among authors: roodhart jml. Science. 2024 May 17;384(6697):785-792. doi: 10.1126/science.adh7950. Epub 2024 May 16. Science. 2024. PMID: 38753784
Extrahepatic perfusion and incomplete hepatic perfusion after hepatic arterial infusion pump implantation: incidence and clinical implications.
Filipe WF, Buisman FE, Franssen S, Krul MF, Grünhagen DJ, Bennink RJ, Bolhuis K, Bruijnen RCG, Buffart TE, Burgmans MC, van Delden OM, Doornebosch PG, Gobardhan PD, Graven L, de Groot JWB, Grootscholten C, Hagendoorn J, Harmsen P, Homs MYV, Klompenhouwer EG, Kok NFM, Lam MGEH, Loosveld OJL, Meier MAJ, Mieog JSD, Oostdijk AHJ, Outmani L, Patijn GA, Pool S, Rietbergen DDD, Roodhart JML, Speetjens FM, Swijnenburg RJ, Versleijen MWJ, Verhoef C, Kuhlmann KFD, Moelker A, Groot Koerkamp B; Dutch HAIP consortium. Filipe WF, et al. Among authors: roodhart jml. HPB (Oxford). 2024 Mar 20:S1365-182X(24)01231-0. doi: 10.1016/j.hpb.2024.03.1158. Online ahead of print. HPB (Oxford). 2024. PMID: 38604828 Free article.
Epidermal growth factor receptor (EGFR) is a target of the tumor-suppressor E3 ligase FBXW7.
Boretto M, Geurts MH, Gandhi S, Ma Z, Staliarova N, Celotti M, Lim S, He GW, Millen R, Driehuis E, Begthel H, Smabers L, Roodhart J, van Es J, Wu W, Clevers H. Boretto M, et al. Among authors: roodhart j. Proc Natl Acad Sci U S A. 2024 Mar 19;121(12):e2309902121. doi: 10.1073/pnas.2309902121. Epub 2024 Mar 14. Proc Natl Acad Sci U S A. 2024. PMID: 38483988 Free PMC article.
Trastuzumab plus pertuzumab for HER2-amplified advanced colorectal cancer: Results from the drug rediscovery protocol (DRUP).
Spiekman IAC, Zeverijn LJ, Geurts BS, Verkerk K, Haj Mohammad SF, van der Noort V, Roepman P, de Leng WWJ, Jansen AML, Gootjes EC, de Groot DA, Kerver ED, van Voorthuizen T, Roodhart JML, Valkenburg-van Iersel LBJ, Gelderblom H, Voest EE, Verheul HMW. Spiekman IAC, et al. Among authors: roodhart jml. Eur J Cancer. 2024 May;202:113988. doi: 10.1016/j.ejca.2024.113988. Epub 2024 Mar 7. Eur J Cancer. 2024. PMID: 38471288 Free article.
Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response.
Smabers LP, Wensink E, Verissimo CS, Koedoot E, Pitsa KC, Huismans MA, Higuera Barón C, Doorn M, Valkenburg-van Iersel LB, Cirkel GA, Brousali A, Overmeer R, Koopman M, Braat MN, Penning de Vries B, Elias SG, Vries RG, Kranenburg O, Boj SF, Roodhart JM. Smabers LP, et al. Among authors: roodhart jm. J Exp Clin Cancer Res. 2024 Feb 27;43(1):61. doi: 10.1186/s13046-024-02980-6. J Exp Clin Cancer Res. 2024. PMID: 38414064 Free PMC article.
73 results