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Prevalence of Baseline Cardiac Arrhythmias in Participants with Overweight or Obesity in Phase 1 Clinical Trials: Analysis of 24-Hour Holter Electrocardiogram Recordings.
J Clin Pharmacol. 2023 May;63(5):539-543. doi: 10.1002/jcph.2193. Epub 2023 Jan 20.
J Clin Pharmacol. 2023.
PMID: 36524539
Clinical Trial.
Results from three phase 1 trials of NNC9204-1177, a glucagon/GLP-1 receptor co-agonist: Effects on weight loss and safety in adults with overweight or obesity.
Friedrichsen MH, Endahl L, Kreiner FF, Goldwater R, Kankam M, Toubro S, Nygård SB.
Friedrichsen MH, et al.
Mol Metab. 2023 Dec;78:101801. doi: 10.1016/j.molmet.2023.101801. Epub 2023 Sep 9.
Mol Metab. 2023.
PMID: 37690519
Free PMC article.
Clinical Trial.
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In vitro CYP450 enzyme down-regulation by GLP-1/glucagon co-agonist does not translate to observed drug-drug interactions in the clinic.
Säll C, Alifrangis L, Dahl K, Friedrichsen MH, Nygård SB, Kristensen K.
Säll C, et al. Among authors: friedrichsen mh.
Drug Metab Dispos. 2022 Jun 9:DMD-AR-2022-000865. doi: 10.1124/dmd.122.000865. Online ahead of print.
Drug Metab Dispos. 2022.
PMID: 35680133
Free article.
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