Grossman TH - Search Results

1

Engineering a "detect and destroy" skin probiotic to combat methicillin-resistant Staphylococcus aureus.

Guan C, Larson PJ, Fleming E, Tikhonov AP, Mootien S, Grossman TH, Golino C, Oh J. Guan C, et al. Among authors: grossman th. PLoS One. 2022 Dec 15;17(12):e0276795. doi: 10.1371/journal.pone.0276795. eCollection 2022. PLoS One. 2022. PMID: 36520793 Free PMC article.

2

Controlling the Growth of the Skin Commensal Staphylococcus epidermidis Using d-Alanine Auxotrophy.

Dodds D, Bose JL, Deng MD, Dubé GR, Grossman TH, Kaiser A, Kulkarni K, Leger R, Mootien-Boyd S, Munivar A, Oh J, Pestrak M, Rajpura K, Tikhonov AP, Turecek T, Whitfill T. Dodds D, et al. Among authors: grossman th. mSphere. 2020 Jun 10;5(3):e00360-20. doi: 10.1128/mSphere.00360-20. mSphere. 2020. PMID: 32522780 Free PMC article.

3

Evaluation of the In Vitro Activity of Eravacycline against a Broad Spectrum of Recent Clinical Anaerobic Isolates.

Snydman DR, McDermott LA, Jacobus NV, Kerstein K, Grossman TH, Sutcliffe JA. Snydman DR, et al. Among authors: grossman th. Antimicrob Agents Chemother. 2018 Apr 26;62(5):e02206-17. doi: 10.1128/AAC.02206-17. Print 2018 May. Antimicrob Agents Chemother. 2018. PMID: 29483114 Free PMC article.

4

The Fluorocycline TP-271 Is Efficacious in Models of Aerosolized Bacillus anthracis Infection in BALB/c Mice and Cynomolgus Macaques.

Grossman TH, Anderson MS, Drabek L, Gooldy M, Heine HS, Henning LN, Lin W, Newman JV, Nevarez R, Siefkas-Patterson K, Radcliff AK, Sutcliffe JA. Grossman TH, et al. Antimicrob Agents Chemother. 2017 Sep 22;61(10):e01103-17. doi: 10.1128/AAC.01103-17. Print 2017 Oct. Antimicrob Agents Chemother. 2017. PMID: 28784679 Free PMC article.

5

Heterocyclyl tetracyclines. 2. 7-Methoxy-8-pyrrolidinyltetracyclines: discovery of TP-2758, a potent, orally efficacious antimicrobial against Gram-negative pathogens.

Sun C, Deng Y, Hunt DK, Fyfe C, Chen CL, Clark RB, Grossman TH, Sutcliffe JA, Xiao XY. Sun C, et al. Among authors: grossman th. J Antibiot (Tokyo). 2018 Feb;71(2):287-297. doi: 10.1038/ja.2017.86. Epub 2017 Jul 26. J Antibiot (Tokyo). 2018. PMID: 28743974

6

The Fluorocycline TP-271 Is Efficacious in Models of Aerosolized Francisella tularensis SCHU S4 Infection in BALB/c Mice and Cynomolgus Macaques.

Grossman TH, Anderson MS, Christ D, Gooldy M, Henning LN, Heine HS, Kindt MV, Lin W, Siefkas-Patterson K, Radcliff AK, Tam VH, Sutcliffe JA. Grossman TH, et al. Antimicrob Agents Chemother. 2017 Jul 25;61(8):e00448-17. doi: 10.1128/AAC.00448-17. Print 2017 Aug. Antimicrob Agents Chemother. 2017. PMID: 28559261 Free PMC article.

7

Fluorocycline TP-271 Is Potent against Complicated Community-Acquired Bacterial Pneumonia Pathogens.

Grossman TH, Fyfe C, O'Brien W, Hackel M, Minyard MB, Waites KB, Dubois J, Murphy TM, Slee AM, Weiss WJ, Sutcliffe JA. Grossman TH, et al. mSphere. 2017 Feb 22;2(1):e00004-17. doi: 10.1128/mSphere.00004-17. eCollection 2017 Jan-Feb. mSphere. 2017. PMID: 28251179 Free PMC article.

8

Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa.

Deng Y, Sun C, Hunt DK, Fyfe C, Chen CL, Grossman TH, Sutcliffe JA, Xiao XY. Deng Y, et al. Among authors: grossman th. J Med Chem. 2017 Mar 23;60(6):2498-2512. doi: 10.1021/acs.jmedchem.6b01903. Epub 2017 Mar 15. J Med Chem. 2017. PMID: 28248499

9

Eravacycline Is Active against Bacterial Isolates Expressing the Polymyxin Resistance Gene mcr-1.

Fyfe C, LeBlanc G, Close B, Nordmann P, Dumas J, Grossman TH. Fyfe C, et al. Among authors: grossman th. Antimicrob Agents Chemother. 2016 Oct 21;60(11):6989-6990. doi: 10.1128/AAC.01646-16. Print 2016 Nov. Antimicrob Agents Chemother. 2016. PMID: 27550359 Free PMC article. No abstract available.

10

Resistance to Macrolide Antibiotics in Public Health Pathogens.

Fyfe C, Grossman TH, Kerstein K, Sutcliffe J. Fyfe C, et al. Among authors: grossman th. Cold Spring Harb Perspect Med. 2016 Oct 3;6(10):a025395. doi: 10.1101/cshperspect.a025395. Cold Spring Harb Perspect Med. 2016. PMID: 27527699 Free PMC article. Review.

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