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Familial atrial fibrillation mutation M1875T-SCN5A increases early sodium current and dampens the effect of flecainide.
O'Reilly M, Sommerfeld LC, O'Shea C, Broadway-Stringer S, Andaleeb S, Reyat JS, Kabir SN, Stastny D, Malinova A, Delbue D, Fortmueller L, Gehmlich K, Pavlovic D, Skryabin BV, Holmes AP, Kirchhof P, Fabritz L. O'Reilly M, et al. Among authors: reyat js. Europace. 2023 Mar 30;25(3):1152-1161. doi: 10.1093/europace/euac218. Europace. 2023. PMID: 36504385 Free PMC article.
Tspan18 is a novel regulator of the Ca2+ channel Orai1 and von Willebrand factor release in endothelial cells.
Noy PJ, Gavin RL, Colombo D, Haining EJ, Reyat JS, Payne H, Thielmann I, Lokman AB, Neag G, Yang J, Lloyd T, Harrison N, Heath VL, Gardiner C, Whitworth KM, Robinson J, Koo CZ, Di Maio A, Harrison P, Lee SP, Michelangeli F, Kalia N, Rainger GE, Nieswandt B, Brill A, Watson SP, Tomlinson MG. Noy PJ, et al. Among authors: reyat js. Haematologica. 2019 Sep;104(9):1892-1905. doi: 10.3324/haematol.2018.194241. Epub 2018 Dec 20. Haematologica. 2019. PMID: 30573509 Free PMC article.
Epigenetic and Transcriptional Networks Underlying Atrial Fibrillation.
van Ouwerkerk AF, Hall AW, Kadow ZA, Lazarevic S, Reyat JS, Tucker NR, Nadadur RD, Bosada FM, Bianchi V, Ellinor PT, Fabritz L, Martin JF, de Laat W, Kirchhof P, Moskowitz IP, Christoffels VM. van Ouwerkerk AF, et al. Among authors: reyat js. Circ Res. 2020 Jun 19;127(1):34-50. doi: 10.1161/CIRCRESAHA.120.316574. Epub 2020 Jun 18. Circ Res. 2020. PMID: 32717170 Free PMC article. Review.
Atrial resting membrane potential confers sodium current sensitivity to propafenone, flecainide and dronedarone.
Holmes AP, Saxena P, Kabir SN, O'Shea C, Kuhlmann SM, Gupta S, Fobian D, Apicella C, O'Reilly M, Syeda F, Reyat JS, Smith GL, Workman AJ, Pavlovic D, Fabritz L, Kirchhof P. Holmes AP, et al. Among authors: reyat js. Heart Rhythm. 2021 Jul;18(7):1212-1220. doi: 10.1016/j.hrthm.2021.03.016. Epub 2021 Mar 16. Heart Rhythm. 2021. PMID: 33737232 Free PMC article.
Increased atrial effectiveness of flecainide conferred by altered biophysical properties of sodium channels.
O' Brien S, Holmes AP, Johnson DM, Kabir SN, O' Shea C, O' Reilly M, Avezzu A, Reyat JS, Hall AW, Apicella C, Ellinor PT, Niederer S, Tucker NR, Fabritz L, Kirchhof P, Pavlovic D. O' Brien S, et al. Among authors: reyat js. J Mol Cell Cardiol. 2022 May;166:23-35. doi: 10.1016/j.yjmcc.2022.01.009. Epub 2022 Feb 1. J Mol Cell Cardiol. 2022. PMID: 35114252 Free article.
Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2.
Broadway-Stringer S, Jiang H, Wadmore K, Hooper C, Douglas G, Steeples V, Azad AJ, Singer E, Reyat JS, Galatik F, Ehler E, Bennett P, Kalisch-Smith JI, Sparrow DB, Davies B, Djinovic-Carugo K, Gautel M, Watkins H, Gehmlich K. Broadway-Stringer S, et al. Among authors: reyat js. Cells. 2023 Feb 24;12(5):721. doi: 10.3390/cells12050721. Cells. 2023. PMID: 36899856 Free PMC article.
An angiopoietin 2, FGF23, and BMP10 biomarker signature differentiates atrial fibrillation from other concomitant cardiovascular conditions.
Chua W, Cardoso VR, Guasch E, Sinner MF, Al-Taie C, Brady P, Casadei B, Crijns HJGM, Dudink EAMP, Hatem SN, Kääb S, Kastner P, Mont L, Nehaj F, Purmah Y, Reyat JS, Schotten U, Sommerfeld LC, Zeemering S, Ziegler A, Gkoutos GV, Kirchhof P, Fabritz L. Chua W, et al. Among authors: reyat js. Sci Rep. 2023 Oct 5;13(1):16743. doi: 10.1038/s41598-023-42331-7. Sci Rep. 2023. PMID: 37798357 Free PMC article.
20 results