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Correction to "Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction".
J Med Chem. 2023 Feb 9;66(3):2204. doi: 10.1021/acs.jmedchem.3c00037. Epub 2023 Jan 26.
J Med Chem. 2023.
PMID: 36701206
Free PMC article.
No abstract available.
Structural Basis of Cysteine Ligase MshC Inhibition by Cysteinyl-Sulfonamides.
Pang L, Lenders S, Osipov EM, Weeks SD, Rozenski J, Piller T, Cappoen D, Strelkov SV, Van Aerschot A.
Pang L, et al. Among authors: lenders s.
Int J Mol Sci. 2022 Dec 1;23(23):15095. doi: 10.3390/ijms232315095.
Int J Mol Sci. 2022.
PMID: 36499418
Free PMC article.
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Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction.
Begnini F, Geschwindner S, Johansson P, Wissler L, Lewis RJ, Danelius E, Luttens A, Matricon P, Carlsson J, Lenders S, König B, Friedel A, Sjö P, Schiesser S, Kihlberg J.
Begnini F, et al. Among authors: lenders s.
J Med Chem. 2022 Feb 24;65(4):3473-3517. doi: 10.1021/acs.jmedchem.1c01975. Epub 2022 Feb 2.
J Med Chem. 2022.
PMID: 35108001
Free PMC article.
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Data driven evaluation of healthy volunteer characteristics at screening for phase I clinical trials to inform on study design and optimize screening processes.
Deiteren A, Coenen E, Lenders S, Verwilst P, Mannaert E, Rasschaert F.
Deiteren A, et al. Among authors: lenders s.
Clin Transl Sci. 2021 Nov;14(6):2450-2460. doi: 10.1111/cts.13113. Epub 2021 Aug 11.
Clin Transl Sci. 2021.
PMID: 34378856
Free PMC article.
Clinical Trial.
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Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors.
De Ruysscher D, Pang L, Lenders SMG, Cappoen D, Cos P, Rozenski J, Strelkov SV, Weeks SD, Van Aerschot A.
De Ruysscher D, et al. Among authors: lenders smg.
Eur J Med Chem. 2021 Feb 5;211:113021. doi: 10.1016/j.ejmech.2020.113021. Epub 2020 Nov 16.
Eur J Med Chem. 2021.
PMID: 33248851
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Facile Synthesis of Aminomethyl Phosphinate Esters as Serine Protease Inhibitors with Primed Site Interaction.
Kahler JP, Lenders S, van de Plassche MAT, Verhelst SHL.
Kahler JP, et al. Among authors: lenders s.
ACS Med Chem Lett. 2020 Aug 10;11(9):1739-1744. doi: 10.1021/acsmedchemlett.0c00284. eCollection 2020 Sep 10.
ACS Med Chem Lett. 2020.
PMID: 32944141
Free PMC article.
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Adjustments of the Pesticide Risk Index Used in Environmental Policy in Flanders.
Fevery D, Peeters B, Lenders S, Spanoghe P.
Fevery D, et al. Among authors: lenders s.
PLoS One. 2015 Jun 5;10(6):e0129669. doi: 10.1371/journal.pone.0129669. eCollection 2015.
PLoS One. 2015.
PMID: 26046655
Free PMC article.
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