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Discovery of a small molecule ligand of FRS2 that inhibits invasion and tumor growth.
Santhana Kumar K, Brunner C, Schuster M, Kopp LL, Gries A, Yan S, Jurt S, Moehle K, Bruns D, Grotzer M, Zerbe O, Schneider G, Baumgartner M. Santhana Kumar K, et al. Among authors: brunner c. Cell Oncol (Dordr). 2023 Apr;46(2):331-356. doi: 10.1007/s13402-022-00753-x. Epub 2022 Dec 10. Cell Oncol (Dordr). 2023. PMID: 36495366 Free PMC article.
De Novo Fragment Design for Drug Discovery and Chemical Biology.
Rodrigues T, Reker D, Welin M, Caldera M, Brunner C, Gabernet G, Schneider P, Walse B, Schneider G. Rodrigues T, et al. Among authors: brunner c. Angew Chem Int Ed Engl. 2015 Dec 7;54(50):15079-83. doi: 10.1002/anie.201508055. Epub 2015 Oct 21. Angew Chem Int Ed Engl. 2015. PMID: 26486226
A novel FRET peptide assay reveals efficient Helicobacter pylori HtrA inhibition through zinc and copper binding.
Bernegger S, Brunner C, Vizovišek M, Fonovic M, Cuciniello G, Giordano F, Stanojlovic V, Jarzab M, Simister P, Feller SM, Obermeyer G, Posselt G, Turk B, Cabrele C, Schneider G, Wessler S. Bernegger S, et al. Among authors: brunner c. Sci Rep. 2020 Jun 29;10(1):10563. doi: 10.1038/s41598-020-67578-2. Sci Rep. 2020. PMID: 32601479 Free PMC article.
High-mass MALDI-MS unravels ligand-mediated G protein-coupling selectivity to GPCRs.
Wu N, Olechwier AM, Brunner C, Edwards PC, Tsai CJ, Tate CG, Schertler GFX, Schneider G, Deupi X, Zenobi R, Ma P. Wu N, et al. Among authors: brunner c. Proc Natl Acad Sci U S A. 2021 Aug 3;118(31):e2024146118. doi: 10.1073/pnas.2024146118. Proc Natl Acad Sci U S A. 2021. PMID: 34326250 Free PMC article.
431 results