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Translational opportunities of single-cell biology in atherosclerosis.
de Winther MPJ, Bäck M, Evans P, Gomez D, Goncalves I, Jørgensen HF, Koenen RR, Lutgens E, Norata GD, Osto E, Dib L, Simons M, Stellos K, Ylä-Herttuala S, Winkels H, Bochaton-Piallat ML, Monaco C. de Winther MPJ, et al. Among authors: lutgens e. Eur Heart J. 2023 Apr 7;44(14):1216-1230. doi: 10.1093/eurheartj/ehac686. Eur Heart J. 2023. PMID: 36478058 Free PMC article. Review.
Disruption of the cathepsin K gene reduces atherosclerosis progression and induces plaque fibrosis but accelerates macrophage foam cell formation.
Lutgens E, Lutgens SP, Faber BC, Heeneman S, Gijbels MM, de Winther MP, Frederik P, van der Made I, Daugherty A, Sijbers AM, Fisher A, Long CJ, Saftig P, Black D, Daemen MJ, Cleutjens KB. Lutgens E, et al. Among authors: lutgens sp. Circulation. 2006 Jan 3;113(1):98-107. doi: 10.1161/CIRCULATIONAHA.105.561449. Epub 2005 Dec 19. Circulation. 2006. PMID: 16365196
Abrogated transforming growth factor beta receptor II (TGFβRII) signalling in dendritic cells promotes immune reactivity of T cells resulting in enhanced atherosclerosis.
Lievens D, Habets KL, Robertson AK, Laouar Y, Winkels H, Rademakers T, Beckers L, Wijnands E, Boon L, Mosaheb M, Ait-Oufella H, Mallat Z, Flavell RA, Rudling M, Binder CJ, Gerdes N, Biessen EA, Weber C, Daemen MJ, Kuiper J, Lutgens E. Lievens D, et al. Among authors: lutgens e. Eur Heart J. 2013 Dec;34(48):3717-27. doi: 10.1093/eurheartj/ehs106. Epub 2012 May 21. Eur Heart J. 2013. PMID: 22613345 Free PMC article.
Distribution of macrophage polarization markers in human atherosclerosis.
Stöger JL, Gijbels MJ, van der Velden S, Manca M, van der Loos CM, Biessen EA, Daemen MJ, Lutgens E, de Winther MP. Stöger JL, et al. Among authors: lutgens e. Atherosclerosis. 2012 Dec;225(2):461-8. doi: 10.1016/j.atherosclerosis.2012.09.013. Epub 2012 Sep 26. Atherosclerosis. 2012. PMID: 23078881 Free article.
240 results