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The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities.
Jiménez-Panizo A, Alegre-Martí A, Tettey TT, Fettweis G, Abella M, Antón R, Johnson TA, Kim S, Schiltz RL, Núñez-Barrios I, Font-Díaz J, Caelles C, Valledor AF, Pérez P, Rojas AM, Fernández-Recio J, Presman DM, Hager GL, Fuentes-Prior P, Estébanez-Perpiñá E. Jiménez-Panizo A, et al. Among authors: estebanez perpina e. Nucleic Acids Res. 2022 Dec 9;50(22):13063-13082. doi: 10.1093/nar/gkac1119. Nucleic Acids Res. 2022. PMID: 36464162 Free PMC article.
Perspectives on designs of antiandrogens for prostate cancer.
Estébanez-Perpiñá E, Jouravel N, Fletterick RJ. Estébanez-Perpiñá E, et al. Expert Opin Drug Discov. 2007 Oct;2(10):1341-55. doi: 10.1517/17460441.2.10.1341. Expert Opin Drug Discov. 2007. PMID: 23484530
Coregulator control of androgen receptor action by a novel nuclear receptor-binding motif.
Jehle K, Cato L, Neeb A, Muhle-Goll C, Jung N, Smith EW, Buzon V, Carbó LR, Estébanez-Perpiñá E, Schmitz K, Fruk L, Luy B, Chen Y, Cox MB, Bräse S, Brown M, Cato AC. Jehle K, et al. J Biol Chem. 2014 Mar 28;289(13):8839-51. doi: 10.1074/jbc.M113.534859. Epub 2014 Feb 12. J Biol Chem. 2014. PMID: 24523409 Free PMC article.
A surface on the androgen receptor that allosterically regulates coactivator binding.
Estébanez-Perpiñá E, Arnold LA, Nguyen P, Rodrigues ED, Mar E, Bateman R, Pallai P, Shokat KM, Baxter JD, Guy RK, Webb P, Fletterick RJ. Estébanez-Perpiñá E, et al. Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16074-9. doi: 10.1073/pnas.0708036104. Epub 2007 Oct 2. Proc Natl Acad Sci U S A. 2007. PMID: 17911242 Free PMC article.
Allosteric conversation in the androgen receptor ligand-binding domain surfaces.
Grosdidier S, Carbó LR, Buzón V, Brooke G, Nguyen P, Baxter JD, Bevan C, Webb P, Estébanez-Perpiñá E, Fernández-Recio J. Grosdidier S, et al. Mol Endocrinol. 2012 Jul;26(7):1078-90. doi: 10.1210/me.2011-1281. Epub 2012 May 31. Mol Endocrinol. 2012. PMID: 22653923 Free PMC article.
36 results