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The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities.
Jiménez-Panizo A, Alegre-Martí A, Tettey TT, Fettweis G, Abella M, Antón R, Johnson TA, Kim S, Schiltz RL, Núñez-Barrios I, Font-Díaz J, Caelles C, Valledor AF, Pérez P, Rojas AM, Fernández-Recio J, Presman DM, Hager GL, Fuentes-Prior P, Estébanez-Perpiñá E. Jiménez-Panizo A, et al. Among authors: caelles c. Nucleic Acids Res. 2022 Dec 9;50(22):13063-13082. doi: 10.1093/nar/gkac1119. Nucleic Acids Res. 2022. PMID: 36464162 Free PMC article.
Distinct Responses to IL4 in Macrophages Mediated by JNK.
Arpa L, Batlle C, Jiang P, Caelles C, Lloberas J, Celada A. Arpa L, et al. Among authors: caelles c. Cells. 2023 Apr 11;12(8):1127. doi: 10.3390/cells12081127. Cells. 2023. PMID: 37190036 Free PMC article.
Pharmacologic Activation of LXR Alters the Expression Profile of Tumor-Associated Macrophages and the Abundance of Regulatory T Cells in the Tumor Microenvironment.
Carbó JM, León TE, Font-Díaz J, De la Rosa JV, Castrillo A, Picard FR, Staudenraus D, Huber M, Cedó L, Escolà-Gil JC, Campos L, Bakiri L, Wagner EF, Caelles C, Stratmann T, Van Ginderachter JA, Valledor AF. Carbó JM, et al. Among authors: caelles c. Cancer Res. 2021 Feb 15;81(4):968-985. doi: 10.1158/0008-5472.CAN-19-3360. Epub 2020 Dec 23. Cancer Res. 2021. PMID: 33361391 Free article.
The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism.
Matalonga J, Glaria E, Bresque M, Escande C, Carbó JM, Kiefer K, Vicente R, León TE, Beceiro S, Pascual-García M, Serret J, Sanjurjo L, Morón-Ros S, Riera A, Paytubi S, Juarez A, Sotillo F, Lindbom L, Caelles C, Sarrias MR, Sancho J, Castrillo A, Chini EN, Valledor AF. Matalonga J, et al. Among authors: caelles c. Cell Rep. 2017 Jan 31;18(5):1241-1255. doi: 10.1016/j.celrep.2017.01.007. Cell Rep. 2017. PMID: 28147278 Free article.
The histone demethylase PHF8 is a molecular safeguard of the IFNγ response.
Asensio-Juan E, Fueyo R, Pappa S, Iacobucci S, Badosa C, Lois S, Balada M, Bosch-Presegué L, Vaquero A, Gutiérrez S, Caelles C, Gallego C, de la Cruz X, Martínez-Balbás MA. Asensio-Juan E, et al. Among authors: caelles c. Nucleic Acids Res. 2017 Apr 20;45(7):3800-3811. doi: 10.1093/nar/gkw1346. Nucleic Acids Res. 2017. PMID: 28100697 Free PMC article.
Over-expression of muscle glycogen synthase in human diabetic nephropathy.
Gatica R, Bertinat R, Silva P, Kairath P, Slebe F, Pardo F, Ramírez MJ, Slebe JC, Campistol JM, Nualart F, Caelles C, Yáñez AJ. Gatica R, et al. Among authors: caelles c. Histochem Cell Biol. 2015 Mar;143(3):313-24. doi: 10.1007/s00418-014-1290-2. Epub 2014 Nov 5. Histochem Cell Biol. 2015. PMID: 25371328
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