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Chronic treatment with the anti-diabetic drug metformin rescues impaired brain mitochondrial activity and selectively ameliorates defective cognitive flexibility in a female mouse model of Rett syndrome.
Urbinati C, Lanzillotta C, Cosentino L, Valenti D, Quattrini MC, Di Crescenzo L, Prestia F, Pietraforte D, Perluigi M, Di Domenico F, Vacca RA, De Filippis B. Urbinati C, et al. Among authors: de filippis b. Neuropharmacology. 2023 Feb 15;224:109350. doi: 10.1016/j.neuropharm.2022.109350. Epub 2022 Nov 25. Neuropharmacology. 2023. PMID: 36442649
Mitochondrial free radical overproduction due to respiratory chain impairment in the brain of a mouse model of Rett syndrome: protective effect of CNF1.
De Filippis B, Valenti D, de Bari L, De Rasmo D, Musto M, Fabbri A, Ricceri L, Fiorentini C, Laviola G, Vacca RA. De Filippis B, et al. Among authors: de bari l, de rasmo d. Free Radic Biol Med. 2015 Jun;83:167-77. doi: 10.1016/j.freeradbiomed.2015.02.014. Epub 2015 Feb 20. Free Radic Biol Med. 2015. PMID: 25708779
Modulation of Rho GTPases rescues brain mitochondrial dysfunction, cognitive deficits and aberrant synaptic plasticity in female mice modeling Rett syndrome.
De Filippis B, Valenti D, Chiodi V, Ferrante A, de Bari L, Fiorentini C, Domenici MR, Ricceri L, Vacca RA, Fabbri A, Laviola G. De Filippis B, et al. Among authors: de bari l. Eur Neuropsychopharmacol. 2015 Jun;25(6):889-901. doi: 10.1016/j.euroneuro.2015.03.012. Epub 2015 Mar 30. Eur Neuropsychopharmacol. 2015. PMID: 25890884
Genes and sex hormones interaction in neurodevelopmental disorders.
Romano E, Cosentino L, Laviola G, De Filippis B. Romano E, et al. Among authors: de filippis b. Neurosci Biobehav Rev. 2016 Aug;67:9-24. doi: 10.1016/j.neubiorev.2016.02.019. Epub 2016 Mar 4. Neurosci Biobehav Rev. 2016. PMID: 26952805 Review.
108 results