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2,8-Dihydroxyadenine-induced nephropathy causes hexosylceramide accumulation with increased mTOR signaling, reduced levels of protective SirT3 expression and impaired renal mitochondrial function.
Moellmann J, Krueger K, Wong DWL, Klinkhammer BM, Buhl EM, Dehairs J, Swinnen JV, Noels H, Jankowski J, Lebherz C, Boor P, Marx N, Lehrke M. Moellmann J, et al. Among authors: marx n. Biochim Biophys Acta Mol Basis Dis. 2024 Jan;1870(1):166825. doi: 10.1016/j.bbadis.2023.166825. Epub 2023 Aug 1. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 37536502 Free article.
Coronary microvascular dysfunction as assessed by angiography-derived index of microvascular resistance co-localizes with and may explain the presence of ischemia in stress-cardiac magnetic resonance imaging in the absence of coronary artery disease.
Milzi A, Dettori R, Lubberich RK, Burgmaier K, Marx N, Reith S, Burgmaier M. Milzi A, et al. Among authors: marx n. Front Cardiovasc Med. 2022 Nov 24;9:1060764. doi: 10.3389/fcvm.2022.1060764. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 36505374 Free PMC article.
Increased levels of a mycophenolic acid metabolite in patients with kidney failure negatively affect cardiomyocyte health.
Harlacher E, Schulte C, Vondenhoff S, Schmitt-Kopplin P, Diederich P, Hemmers C, Moellmann J, Wollenhaupt J, Veltrop R, Biessen E, Lehrke M, Peters B, Schlieper G, Kuppe C, Floege J, Jankowski V, Marx N, Jankowski J, Noels H. Harlacher E, et al. Among authors: marx n. Front Cardiovasc Med. 2024 Mar 6;11:1346475. doi: 10.3389/fcvm.2024.1346475. eCollection 2024. Front Cardiovasc Med. 2024. PMID: 38510194 Free PMC article.
593 results