Smrcka AV - Search Results

1

Phospholipase Cε insufficiency causes ascending aortic aneurysm and dissection.

Atchison DK, O'Connor CL, Converso-Baran K, Bergin IL, Zhang H, Wang Y, Hartman JR, Ju W, Smrcka AV, Ganesh SK, Bitzer M. Atchison DK, et al. Among authors: smrcka av. Am J Physiol Heart Circ Physiol. 2022 Dec 1;323(6):H1376-H1387. doi: 10.1152/ajpheart.00262.2022. Epub 2022 Nov 11. Am J Physiol Heart Circ Physiol. 2022. PMID: 36367690 Free PMC article.

2

Internalized β2-Adrenergic Receptors Inhibit Subcellular Phospholipase C-Dependent Cardiac Hypertrophic Signaling.

Wei W, Smrcka AV. Wei W, et al. Among authors: smrcka av. bioRxiv [Preprint]. 2023 Jun 9:2023.06.07.544153. doi: 10.1101/2023.06.07.544153. bioRxiv. 2023. PMID: 37333278 Free PMC article. Preprint.

3

Phospholipase C epsilon-1 (PLCƐ1) mediates macrophage activation and protection against tuberculosis.

Gupta A, Thirunavukkarasu S, Rangel-Moreno J, Ahmed M, Swanson RV, Mbandi SK, Smrcka AV, Kaushal D, Scriba TJ, Khader SA. Gupta A, et al. Among authors: smrcka av. Infect Immun. 2024 Apr 9;92(4):e0049523. doi: 10.1128/iai.00495-23. Epub 2024 Mar 7. Infect Immun. 2024. PMID: 38451080

4

Phospholipase C-ε defines a PACAP-stimulated pathway for secretion in the chromaffin cell.

Chen X, Coffman BL, Brindley RL, Galpin JD, Ahern CA, Currie KPM, Smrcka AV, Axelrod D, Anantharam A. Chen X, et al. Among authors: smrcka av. J Neuroendocrinol. 2023 Nov;35(11):e13255. doi: 10.1111/jne.13255. Epub 2023 Mar 27. J Neuroendocrinol. 2023. PMID: 36970756 Free PMC article.

5

A PACAP-activated network for secretion requires coordination of Ca²⁺ influx and Ca²⁺ mobilization.

Chen X, Bell NA, Coffman BL, Rabino AA, Garcia-Mata R, Kammermeier PJ, Yule DI, Axelrod D, Smrcka AV, Giovannucci DR, Anantharam A. Chen X, et al. Among authors: smrcka av. Mol Biol Cell. 2024 May 17:mbcE24020083. doi: 10.1091/mbc.E24-02-0083. Online ahead of print. Mol Biol Cell. 2024. PMID: 38758660

6

Stabilization of Interdomain Interactions in G protein α_i Subunits Determines Gα_i Subtype Signaling Specificity.

Lefevre TJ, Wei W, Mukhaleva E, Venkata SPM, Chandan NR, Abraham S, Li Y, Dessauer CW, Vaidehi N, Smrcka AV. Lefevre TJ, et al. Among authors: smrcka av. bioRxiv [Preprint]. 2023 Apr 6:2023.03.10.532072. doi: 10.1101/2023.03.10.532072. bioRxiv. 2023. PMID: 37066214 Free PMC article. Updated. Preprint.

7

Biasing Gβγ Downstream Signaling with Gallein Inhibits Development of Morphine Tolerance and Potentiates Morphine-Induced nociception in a Tolerant State.

Sanchez GA, Smrcka AV, Jutkiewicz EM. Sanchez GA, et al. Among authors: smrcka av. Mol Pharmacol. 2024 May 20:MOLPHARM-AR-2024-000875. doi: 10.1124/molpharm.124.000875. Online ahead of print. Mol Pharmacol. 2024. PMID: 38769020 Free article.

8

Functional interrogation of cellular Lp(a) uptake by genome-scale CRISPR screening.

Khan TG, Cunha JB, Raut C, Burroughs M, Goonewardena SN, Smrcka AV, Speliotes EK, Emmer BT. Khan TG, et al. Among authors: smrcka av. bioRxiv [Preprint]. 2024 May 12:2024.05.11.593568. doi: 10.1101/2024.05.11.593568. bioRxiv. 2024. PMID: 38766193 Free PMC article. Preprint.

9

Biophysical characterization of the CXC chemokine receptor 2 ligands.

Martin P, Kurth EA, Budean D, Momplaisir N, Qu E, Simien JM, Orellana GE, Brautigam CA, Smrcka AV, Haglund E. Martin P, et al. Among authors: smrcka av. PLoS One. 2024 Apr 16;19(4):e0298418. doi: 10.1371/journal.pone.0298418. eCollection 2024. PLoS One. 2024. PMID: 38625857 Free PMC article.

10

AI is a viable alternative to high throughput screening: a 318-target study.

Atomwise AIMS Program. Atomwise AIMS Program. Sci Rep. 2024 Apr 2;14(1):7526. doi: 10.1038/s41598-024-54655-z. Sci Rep. 2024. PMID: 38565852 Free PMC article.

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