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Phospholipase Cε insufficiency causes ascending aortic aneurysm and dissection.
Atchison DK, O'Connor CL, Converso-Baran K, Bergin IL, Zhang H, Wang Y, Hartman JR, Ju W, Smrcka AV, Ganesh SK, Bitzer M. Atchison DK, et al. Am J Physiol Heart Circ Physiol. 2022 Dec 1;323(6):H1376-H1387. doi: 10.1152/ajpheart.00262.2022. Epub 2022 Nov 11. Am J Physiol Heart Circ Physiol. 2022. PMID: 36367690 Free PMC article.
Hypertension induces glomerulosclerosis in phospholipase C-ε1 deficiency.
Atchison DK, O'Connor CL, Menon R, Otto EA, Ganesh SK, Wiggins RC, Smrcka AV, Bitzer M. Atchison DK, et al. Am J Physiol Renal Physiol. 2020 May 1;318(5):F1177-F1187. doi: 10.1152/ajprenal.00541.2019. Epub 2020 Mar 30. Am J Physiol Renal Physiol. 2020. PMID: 32223311 Free PMC article.
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