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NADPH Oxidase 5 (NOX5) Overexpression Promotes Endothelial Dysfunction via Cell Apoptosis, Migration, and Metabolic Alterations in Human Brain Microvascular Endothelial Cells (hCMEC/D3).
Marqués J, Fernández-Irigoyen J, Ainzúa E, Martínez-Azcona M, Cortés A, Roncal C, Orbe J, Santamaría E, Zalba G. Marqués J, et al. Among authors: roncal c. Antioxidants (Basel). 2022 Oct 29;11(11):2147. doi: 10.3390/antiox11112147. Antioxidants (Basel). 2022. PMID: 36358519 Free PMC article.
Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/reperfusion injury.
Schneider M, Van Geyte K, Fraisl P, Kiss J, Aragonés J, Mazzone M, Mairbäurl H, De Bock K, Jeoung NH, Mollenhauer M, Georgiadou M, Bishop T, Roncal C, Sutherland A, Jordan B, Gallez B, Weitz J, Harris RA, Maxwell P, Baes M, Ratcliffe P, Carmeliet P. Schneider M, et al. Among authors: roncal c. Gastroenterology. 2010 Mar;138(3):1143-54.e1-2. doi: 10.1053/j.gastro.2009.09.057. Epub 2009 Oct 8. Gastroenterology. 2010. PMID: 19818783 Free article.
Gene-targeting of Phd2 improves tumor response to chemotherapy and prevents side-toxicity.
Leite de Oliveira R, Deschoemaeker S, Henze AT, Debackere K, Finisguerra V, Takeda Y, Roncal C, Dettori D, Tack E, Jönsson Y, Veschini L, Peeters A, Anisimov A, Hofmann M, Alitalo K, Baes M, D'hooge J, Carmeliet P, Mazzone M. Leite de Oliveira R, et al. Among authors: roncal c. Cancer Cell. 2012 Aug 14;22(2):263-77. doi: 10.1016/j.ccr.2012.06.028. Cancer Cell. 2012. PMID: 22897855 Free article.
Genetics, epigenetics and pharmaco-(epi)genomics in angiogenesis.
Buysschaert I, Schmidt T, Roncal C, Carmeliet P, Lambrechts D. Buysschaert I, et al. Among authors: roncal c. J Cell Mol Med. 2008 Dec;12(6B):2533-51. doi: 10.1111/j.1582-4934.2008.00515.x. J Cell Mol Med. 2008. PMID: 19210754 Free PMC article. Review.
Targeting VEGFR1 on endothelial progenitors modulates their differentiation potential.
d'Audigier C, Gautier B, Yon A, Alili JM, Guérin CL, Evrard SM, Godier A, Haviari S, Reille-Serroussi M, Huguenot F, Dizier B, Inguimbert N, Borgel D, Bièche I, Boisson-Vidal C, Roncal C, Carmeliet P, Vidal M, Gaussem P, Smadja DM. d'Audigier C, et al. Among authors: roncal c. Angiogenesis. 2014 Jul;17(3):603-16. doi: 10.1007/s10456-013-9413-2. Epub 2014 Jan 14. Angiogenesis. 2014. PMID: 24419917
PHD2 regulates arteriogenic macrophages through TIE2 signalling.
Hamm A, Veschini L, Takeda Y, Costa S, Delamarre E, Squadrito ML, Henze AT, Wenes M, Serneels J, Pucci F, Roncal C, Anisimov A, Alitalo K, De Palma M, Mazzone M. Hamm A, et al. Among authors: roncal c. EMBO Mol Med. 2013 Jun;5(6):843-57. doi: 10.1002/emmm.201302695. Epub 2013 Apr 25. EMBO Mol Med. 2013. PMID: 23616286 Free PMC article.
Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis.
Takeda Y, Costa S, Delamarre E, Roncal C, Leite de Oliveira R, Squadrito ML, Finisguerra V, Deschoemaeker S, Bruyère F, Wenes M, Hamm A, Serneels J, Magat J, Bhattacharyya T, Anisimov A, Jordan BF, Alitalo K, Maxwell P, Gallez B, Zhuang ZW, Saito Y, Simons M, De Palma M, Mazzone M. Takeda Y, et al. Among authors: roncal c. Nature. 2011 Oct 9;479(7371):122-6. doi: 10.1038/nature10507. Nature. 2011. PMID: 21983962 Free PMC article.
97 results