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Identification and Characterization of ACP-5862, the Major Circulating Active Metabolite of Acalabrutinib: Both Are Potent and Selective Covalent Bruton Tyrosine Kinase Inhibitors .
Podoll T, Pearson PG, Kaptein A, Evarts J, de Bruin G, Emmelot-van Hoek M, de Jong A, van Lith B, Sun H, Byard S, Fretland A, Hoogenboom N, Barf T, Slatter JG. Podoll T, et al. Among authors: van lith b. J Pharmacol Exp Ther. 2023 Jan;384(1):173-186. doi: 10.1124/jpet.122.001116. Epub 2022 Oct 30. J Pharmacol Exp Ther. 2023. PMID: 36310034
Healthcare needs, expectations, utilization, and experienced treatment effects in patients with hereditary spastic paraplegia: a web-based survey in the Netherlands.
Kerstens HCJW, Van Lith BJH, Nijkrake MJ, De Swart BJM, Van den Bemd LAC, Smeets RJEM, Klemens F, Van de Warrenburg BPC, Van der Wees PJ, Geurts ACH. Kerstens HCJW, et al. Among authors: van lith bjh. Orphanet J Rare Dis. 2021 Jun 24;16(1):283. doi: 10.1186/s13023-021-01915-0. Orphanet J Rare Dis. 2021. PMID: 34167574 Free PMC article.
Discovery of quinoline-based irreversible BTK inhibitors.
de Bruin G, Demont D, de Zwart E, Verkaik S, Hoogenboom N, van de Kar B, van Lith B, Emmelot-van Hoek M, Gulrajani M, Covey T, Kaptein A, Barf T. de Bruin G, et al. Among authors: van lith b. Bioorg Med Chem Lett. 2020 Jul 15;30(14):127261. doi: 10.1016/j.bmcl.2020.127261. Epub 2020 May 13. Bioorg Med Chem Lett. 2020. PMID: 32527559
Experienced complaints, activity limitations and loss of motor capacities in patients with pure hereditary spastic paraplegia: a web-based survey in the Netherlands.
van Lith BJH, Kerstens HCJW, van den Bemd LAC, der Sanden MWGN, Weerdesteyn V, Smeets RJEM, Fheodoroff K, van de Warrenburg BPC, Geurts ACH. van Lith BJH, et al. Orphanet J Rare Dis. 2020 Mar 4;15(1):64. doi: 10.1186/s13023-020-1338-4. Orphanet J Rare Dis. 2020. PMID: 32131864 Free PMC article.
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