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Digital twin of a continuous direct compression line for drug product and process design using a hybrid flowsheet modelling approach.
Int J Pharm. 2022 Nov 25;628:122336. doi: 10.1016/j.ijpharm.2022.122336. Epub 2022 Oct 26.
Int J Pharm. 2022.
PMID: 36309292
Continuous Mixing Technology: Characterization of a Vertical Mixer Using Residence Time Distribution.
Lee KT, Kimber JA, Cogoni G, Brandon JK, Wilsdon D, Verrier HM, Grieb S, Blackwood DO, Jain AC, Doshi P.
Lee KT, et al. Among authors: verrier hm.
J Pharm Sci. 2021 Jul;110(7):2694-2702. doi: 10.1016/j.xphs.2021.01.035. Epub 2021 Feb 16.
J Pharm Sci. 2021.
PMID: 33607187
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Continuous mixing technology: Validation of a DEM model.
Toson P, Doshi P, Matic M, Siegmann E, Blackwood D, Jain A, Brandon J, Lee K, Wilsdon D, Kimber J, Verrier H, Khinast J, Jajcevic D.
Toson P, et al.
Int J Pharm. 2021 Oct 25;608:121065. doi: 10.1016/j.ijpharm.2021.121065. Epub 2021 Sep 2.
Int J Pharm. 2021.
PMID: 34481005
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Development of a predictive model for gravimetric powder feeding from an API-rich materials properties library.
Shier AP, Kumar A, Mercer A, Majeed N, Doshi P, Blackwood DO, Verrier HM.
Shier AP, et al. Among authors: verrier hm.
Int J Pharm. 2022 Sep 25;625:122071. doi: 10.1016/j.ijpharm.2022.122071. Epub 2022 Aug 3.
Int J Pharm. 2022.
PMID: 35931397
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Towards integrated drug substance and drug product design for an active pharmaceutical ingredient using particle engineering.
Kougoulos E, Smales I, Verrier HM.
Kougoulos E, et al. Among authors: verrier hm.
AAPS PharmSciTech. 2011 Mar;12(1):287-94. doi: 10.1208/s12249-011-9582-5. Epub 2011 Jan 19.
AAPS PharmSciTech. 2011.
PMID: 21246419
Free PMC article.
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Design and synthesis of a functionally selective D3 agonist and its in vivo delivery via the intranasal route.
Blagg J, Allerton CM, Batchelor DV, Baxter AD, Burring DJ, Carr CL, Cook AS, Nichols CL, Phipps J, Sanderson VG, Verrier H, Wong S.
Blagg J, et al.
Bioorg Med Chem Lett. 2007 Dec 15;17(24):6691-6. doi: 10.1016/j.bmcl.2007.10.059. Epub 2007 Oct 22.
Bioorg Med Chem Lett. 2007.
PMID: 17976986
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Discovery of a selective small-molecule melanocortin-4 receptor agonist with efficacy in a pilot study of sexual dysfunction in humans.
Lansdell MI, Hepworth D, Calabrese A, Brown AD, Blagg J, Burring DJ, Wilson P, Fradet D, Brown TB, Quinton F, Mistry N, Tang K, Mount N, Stacey P, Edmunds N, Adams C, Gaboardi S, Neal-Morgan S, Wayman C, Cole S, Phipps J, Lewis M, Verrier H, Gillon V, Feeder N, Heatherington A, Sultana S, Haughie S, Martin SW, Sudworth M, Tweedy S.
Lansdell MI, et al.
J Med Chem. 2010 Apr 22;53(8):3183-97. doi: 10.1021/jm9017866.
J Med Chem. 2010.
PMID: 20329799
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Predictability of intranasal pharmacokinetics in man using pre-clinical pharmacokinetic data with a dopamine 3 receptor agonist, PF-219061.
Attkins NJ, Heatherington AC, Phipps J, Verrier H, Huyghe I.
Attkins NJ, et al.
Xenobiotica. 2009 Jul;39(7):523-33. doi: 10.1080/00498250902893775.
Xenobiotica. 2009.
PMID: 19480558
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