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Regulation of Ferroptosis by Transcription Factor E2F1 and RB.
Res Sq [Preprint]. 2023 Jan 30:rs.3.rs-2493335. doi: 10.21203/rs.3.rs-2493335/v1.
Res Sq. 2023.
PMID: 36778475
Free PMC article.
Preprint.
First-in-Class Dual Mechanism Ferroptosis-HDAC Inhibitor Hybrids.
Karaj E, Sindi SH, Kuganesan N, Koranne RA, Knoff JR, James AW, Fu Y, Kotsull LN, Pflum MK, Shah Z, Taylor WR, Tillekeratne LMV.
Karaj E, et al. Among authors: kuganesan n.
J Med Chem. 2022 Nov 10;65(21):14764-14791. doi: 10.1021/acs.jmedchem.2c01276. Epub 2022 Oct 28.
J Med Chem. 2022.
PMID: 36306372
Free PMC article.
Item in Clipboard
Tunable Cysteine-Targeting Electrophilic Heteroaromatic Warheads Induce Ferroptosis.
Karaj E, Sindi SH, Kuganesan N, Perera L, Taylor W, Tillekeratne LMV.
Karaj E, et al. Among authors: kuganesan n.
J Med Chem. 2022 Sep 8;65(17):11788-11817. doi: 10.1021/acs.jmedchem.2c00909. Epub 2022 Aug 19.
J Med Chem. 2022.
PMID: 35984756
Free PMC article.
Item in Clipboard
Tumor suppressor p53 promotes ferroptosis in oxidative stress conditions independent of modulation of ferroptosis by p21, CDKs, RB, and E2F.
Kuganesan N, Dlamini S, Tillekeratne LMV, Taylor WR.
Kuganesan N, et al.
J Biol Chem. 2021 Dec;297(6):101365. doi: 10.1016/j.jbc.2021.101365. Epub 2021 Oct 30.
J Biol Chem. 2021.
PMID: 34728216
Free PMC article.
Item in Clipboard
Identification and initial characterization of a potent inhibitor of ferroptosis.
Kuganesan N, Dlamini S, McDaniel J, Tillekeratne VLM, Taylor WR.
Kuganesan N, et al.
J Cell Biochem. 2021 Apr;122(3-4):413-424. doi: 10.1002/jcb.29870. Epub 2020 Dec 29.
J Cell Biochem. 2021.
PMID: 33377232
Free PMC article.
Item in Clipboard
Small-Molecule Ferroptotic Agents with Potential to Selectively Target Cancer Stem Cells.
Taylor WR, Fedorka SR, Gad I, Shah R, Alqahtani HD, Koranne R, Kuganesan N, Dlamini S, Rogers T, Al-Hamashi A, Kholodovych V, Barudi Y, Junk D, Rashid MS, Jackson MW, Tillekeratne LMV.
Taylor WR, et al. Among authors: kuganesan n.
Sci Rep. 2019 Apr 11;9(1):5926. doi: 10.1038/s41598-019-42251-5.
Sci Rep. 2019.
PMID: 30976078
Free PMC article.
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