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Determinants and Prediction of Esterase Substrate Promiscuity Patterns.
Martínez-Martínez M, Coscolín C, Santiago G, Chow J, Stogios PJ, Bargiela R, Gertler C, Navarro-Fernández J, Bollinger A, Thies S, Méndez-García C, Popovic A, Brown G, Chernikova TN, García-Moyano A, Bjerga GEK, Pérez-García P, Hai T, Del Pozo MV, Stokke R, Steen IH, Cui H, Xu X, Nocek BP, Alcaide M, Distaso M, Mesa V, Peláez AI, Sánchez J, Buchholz PCF, Pleiss J, Fernández-Guerra A, Glöckner FO, Golyshina OV, Yakimov MM, Savchenko A, Jaeger KE, Yakunin AF, Streit WR, Golyshin PN, Guallar V, Ferrer M, The Inmare Consortium. Martínez-Martínez M, et al. Among authors: ferrer m. ACS Chem Biol. 2018 Jan 19;13(1):225-234. doi: 10.1021/acschembio.7b00996. Epub 2017 Dec 20. ACS Chem Biol. 2018. PMID: 29182315
Rational Engineering of Multiple Active Sites in an Ester Hydrolase.
Santiago G, Martínez-Martínez M, Alonso S, Bargiela R, Coscolín C, Golyshin PN, Guallar V, Ferrer M. Santiago G, et al. Among authors: ferrer m. Biochemistry. 2018 Apr 17;57(15):2245-2255. doi: 10.1021/acs.biochem.8b00274. Epub 2018 Mar 30. Biochemistry. 2018. PMID: 29600855 Free article.
The bone-degrading enzyme machinery: From multi-component understanding to the treatment of residues from the meat industry.
Fernandez-Lopez L, Sanchez-Carrillo S, García-Moyano A, Borchert E, Almendral D, Alonso S, Cea-Rama I, Miguez N, Larsen Ø, Werner J, Makarova KS, Plou FJ, Dahlgren TG, Sanz-Aparicio J, Hentschel U, Bjerga GEK, Ferrer M. Fernandez-Lopez L, et al. Among authors: ferrer m. Comput Struct Biotechnol J. 2021 Nov 23;19:6328-6342. doi: 10.1016/j.csbj.2021.11.027. eCollection 2021. Comput Struct Biotechnol J. 2021. PMID: 34938409 Free PMC article.
A Plurizyme with Transaminase and Hydrolase Activity Catalyzes Cascade Reactions.
Roda S, Fernandez-Lopez L, Benedens M, Bollinger A, Thies S, Schumacher J, Coscolín C, Kazemi M, Santiago G, Gertzen CGW, Gonzalez-Alfonso JL, Plou FJ, Jaeger KE, Smits SHJ, Ferrer M, Guallar V. Roda S, et al. Among authors: ferrer m. Angew Chem Int Ed Engl. 2022 Sep 12;61(37):e202207344. doi: 10.1002/anie.202207344. Epub 2022 Aug 4. Angew Chem Int Ed Engl. 2022. PMID: 35734849 Free PMC article.
Design and Characterization of In-One Protease-Esterase PluriZyme.
Fernandez-Lopez L, Roda S, Gonzalez-Alfonso JL, Plou FJ, Guallar V, Ferrer M. Fernandez-Lopez L, et al. Among authors: ferrer m. Int J Mol Sci. 2022 Nov 1;23(21):13337. doi: 10.3390/ijms232113337. Int J Mol Sci. 2022. PMID: 36362119 Free PMC article.
Transforming an esterase into an enantioselective catecholase through bioconjugation of a versatile metal-chelating inhibitor.
Fernandez-Lopez L, Cea-Rama I, Alvarez-Malmagro J, Ressmann AK, Gonzalez-Alfonso JL, Coscolín C, Shahgaldian P, Plou FJ, Modregger J, Pita M, Sanz-Aparicio J, Ferrer M. Fernandez-Lopez L, et al. Among authors: ferrer m. Chem Commun (Camb). 2023 Aug 1;59(62):9469-9472. doi: 10.1039/d3cc01946b. Chem Commun (Camb). 2023. PMID: 37376994
2,097 results