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Plant Cysteine Oxidase Oxygen-Sensing Function Is Conserved in Early Land Plants and Algae.
Taylor-Kearney LJ, Madden S, Wilson J, Myers WK, Gunawardana DM, Pires E, Holdship P, Tumber A, Rickaby REM, Flashman E. Taylor-Kearney LJ, et al. Among authors: flashman e. ACS Bio Med Chem Au. 2022 Oct 19;2(5):521-528. doi: 10.1021/acsbiomedchemau.2c00032. Epub 2022 Aug 15. ACS Bio Med Chem Au. 2022. PMID: 36281301 Free PMC article.
Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials.
Yeh TL, Leissing TM, Abboud MI, Thinnes CC, Atasoylu O, Holt-Martyn JP, Zhang D, Tumber A, Lippl K, Lohans CT, Leung IKH, Morcrette H, Clifton IJ, Claridge TDW, Kawamura A, Flashman E, Lu X, Ratcliffe PJ, Chowdhury R, Pugh CW, Schofield CJ. Yeh TL, et al. Among authors: flashman e. Chem Sci. 2017 Nov 1;8(11):7651-7668. doi: 10.1039/c7sc02103h. Epub 2017 Sep 11. Chem Sci. 2017. PMID: 29435217 Free PMC article.
Structures of Arabidopsis thaliana oxygen-sensing plant cysteine oxidases 4 and 5 enable targeted manipulation of their activity.
White MD, Dalle Carbonare L, Lavilla Puerta M, Iacopino S, Edwards M, Dunne K, Pires E, Levy C, McDonough MA, Licausi F, Flashman E. White MD, et al. Among authors: flashman e. Proc Natl Acad Sci U S A. 2020 Sep 15;117(37):23140-23147. doi: 10.1073/pnas.2000206117. Epub 2020 Aug 31. Proc Natl Acad Sci U S A. 2020. PMID: 32868422 Free PMC article.
Emerging roles for thiol dioxygenases as oxygen sensors.
Gunawardana DM, Heathcote KC, Flashman E. Gunawardana DM, et al. Among authors: flashman e. FEBS J. 2022 Sep;289(18):5426-5439. doi: 10.1111/febs.16147. Epub 2021 Aug 27. FEBS J. 2022. PMID: 34346181 Free article. Review.
58 results