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Prevention of microgliosis halts early memory loss in a mouse model of Alzheimer's disease.
Brain Behav Immun. 2023 Jan;107:225-241. doi: 10.1016/j.bbi.2022.10.009. Epub 2022 Oct 18.
Brain Behav Immun. 2023.
PMID: 36270437
Free article.
Mechanical alterations of the hippocampus in the APP/PS1 Alzheimer's disease mouse model.
Antonovaite N, Hulshof LA, Huffels CFM, Hol EM, Wadman WJ, Iannuzzi D.
Antonovaite N, et al. Among authors: huffels cfm.
J Mech Behav Biomed Mater. 2021 Oct;122:104697. doi: 10.1016/j.jmbbm.2021.104697. Epub 2021 Jul 10.
J Mech Behav Biomed Mater. 2021.
PMID: 34271406
Free article.
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Systemic Injection of Aged Blood Plasma in Adult C57BL/6 Mice Induces Neurophysiological Impairments in the Hippocampal CA1.
Huffels CFM, van Dijk RE, Karst H, Meye FJ, Hol EM, Middeldorp J.
Huffels CFM, et al.
J Alzheimers Dis. 2022;89(1):283-297. doi: 10.3233/JAD-220337.
J Alzheimers Dis. 2022.
PMID: 35871343
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Aß Pathology and Neuron-Glia Interactions: A Synaptocentric View.
Huffels CFM, Middeldorp J, Hol EM.
Huffels CFM, et al.
Neurochem Res. 2023 Apr;48(4):1026-1046. doi: 10.1007/s11064-022-03699-6. Epub 2022 Aug 17.
Neurochem Res. 2023.
PMID: 35976488
Free PMC article.
Review.
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Calcium signaling in individual APP/PS1 mouse dentate gyrus astrocytes increases ex vivo with Aβ pathology and age without affecting astrocyte network activity.
Huffels CFM, Osborn LM, Cappaert NLM, Hol EM.
Huffels CFM, et al.
J Neurosci Res. 2022 Jun;100(6):1281-1295. doi: 10.1002/jnr.25042. Epub 2022 Mar 16.
J Neurosci Res. 2022.
PMID: 35293016
Free PMC article.
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Amyloid-β plaques affect astrocyte Kir4.1 protein expression but not function in the dentate gyrus of APP/PS1 mice.
Huffels CFM, Osborn LM, Hulshof LA, Kooijman L, Henning L, Steinhäuser C, Hol EM.
Huffels CFM, et al.
Glia. 2022 Apr;70(4):748-767. doi: 10.1002/glia.24137. Epub 2022 Jan 4.
Glia. 2022.
PMID: 34981861
Free PMC article.
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A neuronal mechanism underlying decision-making deficits during hyperdopaminergic states.
Verharen JPH, de Jong JW, Roelofs TJM, Huffels CFM, van Zessen R, Luijendijk MCM, Hamelink R, Willuhn I, den Ouden HEM, van der Plasse G, Adan RAH, Vanderschuren LJMJ.
Verharen JPH, et al. Among authors: huffels cfm.
Nat Commun. 2018 Feb 21;9(1):731. doi: 10.1038/s41467-018-03087-1.
Nat Commun. 2018.
PMID: 29467419
Free PMC article.
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Early amyloid-induced changes in microglia gene expression in male APP/PS1 mice.
Oshima T, Kater MSJ, Huffels CFM, Wesseling EM, Middeldorp J, Hol EM, Verheijen MHG, Smit AB, Boddeke EWGM, Eggen BJL.
Oshima T, et al. Among authors: huffels cfm.
J Neurosci Res. 2024 Mar;102(3):e25295. doi: 10.1002/jnr.25295.
J Neurosci Res. 2024.
PMID: 38515329
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