Oberst A - Search Results

1

Human ZBP1 induces cell death-independent inflammatory signaling via RIPK3 and RIPK1.

Peng R, Wang CK, Wang-Kan X, Idorn M, Kjaer M, Zhou FY, Fiil BK, Timmermann F, Orozco SL, McCarthy J, Leung CS, Lu X, Bagola K, Rehwinkel J, Oberst A, Maelfait J, Paludan SR, Gyrd-Hansen M. Peng R, et al. Among authors: oberst a. EMBO Rep. 2022 Dec 6;23(12):e55839. doi: 10.15252/embr.202255839. Epub 2022 Oct 21. EMBO Rep. 2022. PMID: 36268590 Free PMC article.

2

RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis.

Orozco S, Yatim N, Werner MR, Tran H, Gunja SY, Tait SW, Albert ML, Green DR, Oberst A. Orozco S, et al. Among authors: oberst a. Cell Death Differ. 2014 Oct;21(10):1511-21. doi: 10.1038/cdd.2014.76. Epub 2014 Jun 6. Cell Death Differ. 2014. PMID: 24902904 Free PMC article.

3

RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8⁺ T cells.

Yatim N, Jusforgues-Saklani H, Orozco S, Schulz O, Barreira da Silva R, Reis e Sousa C, Green DR, Oberst A, Albert ML. Yatim N, et al. Among authors: oberst a. Science. 2015 Oct 16;350(6258):328-34. doi: 10.1126/science.aad0395. Epub 2015 Sep 24. Science. 2015. PMID: 26405229 Free PMC article.

4

RIPK3 Restricts Viral Pathogenesis via Cell Death-Independent Neuroinflammation.

Daniels BP, Snyder AG, Olsen TM, Orozco S, Oguin TH 3rd, Tait SWG, Martinez J, Gale M Jr, Loo YM, Oberst A. Daniels BP, et al. Among authors: oberst a. Cell. 2017 Apr 6;169(2):301-313.e11. doi: 10.1016/j.cell.2017.03.011. Epub 2017 Mar 30. Cell. 2017. PMID: 28366204 Free PMC article.

5

RIPK3 in cell death and inflammation: the good, the bad, and the ugly.

Orozco S, Oberst A. Orozco S, et al. Among authors: oberst a. Immunol Rev. 2017 May;277(1):102-112. doi: 10.1111/imr.12536. Immunol Rev. 2017. PMID: 28462521 Free PMC article. Review.

6

Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity.

Snyder AG, Hubbard NW, Messmer MN, Kofman SB, Hagan CE, Orozco SL, Chiang K, Daniels BP, Baker D, Oberst A. Snyder AG, et al. Among authors: oberst a. Sci Immunol. 2019 Jun 21;4(36):eaaw2004. doi: 10.1126/sciimmunol.aaw2004. Sci Immunol. 2019. PMID: 31227597 Free PMC article.

7

RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity.

Orozco SL, Daniels BP, Yatim N, Messmer MN, Quarato G, Chen-Harris H, Cullen SP, Snyder AG, Ralli-Jain P, Frase S, Tait SWG, Green DR, Albert ML, Oberst A. Orozco SL, et al. Among authors: oberst a. Cell Rep. 2019 Aug 27;28(9):2275-2287.e5. doi: 10.1016/j.celrep.2019.07.077. Cell Rep. 2019. PMID: 31461645 Free PMC article.

8

MK2 balances inflammation and cell death.

Oberst A. Oberst A. Nat Cell Biol. 2017 Sep 29;19(10):1150-1152. doi: 10.1038/ncb3619. Nat Cell Biol. 2017. PMID: 28960200

9

Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis.

Riley JS, Quarato G, Cloix C, Lopez J, O'Prey J, Pearson M, Chapman J, Sesaki H, Carlin LM, Passos JF, Wheeler AP, Oberst A, Ryan KM, Tait SW. Riley JS, et al. Among authors: oberst a. EMBO J. 2018 Sep 3;37(17):e99238. doi: 10.15252/embj.201899238. Epub 2018 Jul 26. EMBO J. 2018. PMID: 30049712 Free PMC article.

10

The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons.

Daniels BP, Kofman SB, Smith JR, Norris GT, Snyder AG, Kolb JP, Gao X, Locasale JW, Martinez J, Gale M Jr, Loo YM, Oberst A. Daniels BP, et al. Among authors: oberst a. Immunity. 2019 Jan 15;50(1):64-76.e4. doi: 10.1016/j.immuni.2018.11.017. Epub 2019 Jan 8. Immunity. 2019. PMID: 30635240 Free PMC article.

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