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A Journey through Diastereomeric Space: The Design, Synthesis, In Vitro and In Vivo Pharmacological Activity, and Molecular Modeling of Novel Potent Diastereomeric MOR Agonists and Antagonists.
Molecules. 2022 Sep 30;27(19):6455. doi: 10.3390/molecules27196455.
Molecules. 2022.
PMID: 36234992
Free PMC article.
Structure-Based Design and Development of Chemical Probes Targeting Putative MOR-CCR5 Heterodimers to Inhibit Opioid Exacerbated HIV-1 Infectivity.
Huang B, Wang H, Zheng Y, Li M, Kang G, Barreto-de-Souza V, Nassehi N, Knapp PE, Selley DE, Hauser KF, Zhang Y.
Huang B, et al. Among authors: nassehi n.
J Med Chem. 2021 Jun 10;64(11):7702-7723. doi: 10.1021/acs.jmedchem.1c00408. Epub 2021 May 23.
J Med Chem. 2021.
PMID: 34027668
Free PMC article.
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Novel bivalent ligands carrying potential antinociceptive effects by targeting putative mu opioid receptor and chemokine receptor CXCR4 heterodimers.
Ma H, Li M, Pagare PP, Wang H, Nassehi N, Santos EJ, Stevens Negus S, Selley DE, Zhang Y.
Ma H, et al. Among authors: nassehi n.
Bioorg Chem. 2022 Mar;120:105641. doi: 10.1016/j.bioorg.2022.105641. Epub 2022 Jan 24.
Bioorg Chem. 2022.
PMID: 35093692
Free PMC article.
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Bivalent Ligand Aiming Putative Mu Opioid Receptor and Chemokine Receptor CXCR4 Dimers in Opioid Enhanced HIV-1 Entry.
Ma H, Wang H, Li M, Barreto-de-Souza V, Reinecke BA, Gunta R, Zheng Y, Kang G, Nassehi N, Zhang H, An J, Selley DE, Hauser KF, Zhang Y.
Ma H, et al. Among authors: nassehi n.
ACS Med Chem Lett. 2020 Sep 13;11(11):2318-2324. doi: 10.1021/acsmedchemlett.0c00444. eCollection 2020 Nov 12.
ACS Med Chem Lett. 2020.
PMID: 33214847
Free PMC article.
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Psychedelic-like Properties of Quipazine and Its Structural Analogues in Mice.
de la Fuente Revenga M, Shah UH, Nassehi N, Jaster AM, Hemanth P, Sierra S, Dukat M, González-Maeso J.
de la Fuente Revenga M, et al. Among authors: nassehi n.
ACS Chem Neurosci. 2021 Mar 3;12(5):831-844. doi: 10.1021/acschemneuro.0c00291. Epub 2021 Jan 5.
ACS Chem Neurosci. 2021.
PMID: 33400504
Free PMC article.
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Role of efficacy as a determinant of locomotor activation by mu-opioid receptor (MOR) ligands in female and male mice. II. Effects of novel MOR-selective phenylmorphans with high-to-low MOR efficacy.
Santos EJ, Nassehi N, Bow EW, Chambers DR, Gutman ES, Jacobson AE, Lutz JA, Marsh SA, Rice KC, Sulima A, Selley DE, Negus SS.
Santos EJ, et al. Among authors: nassehi n.
Pharmacol Res Perspect. 2023 Aug;11(4):e01111. doi: 10.1002/prp2.1111.
Pharmacol Res Perspect. 2023.
PMID: 37381112
Free PMC article.
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