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A standardised methodology for the extraction and quantification of cell-free DNA in cerebrospinal fluid and application to evaluation of Alzheimer's disease and brain cancers.
Takousis P, Devonshire AS, Redshaw N, von Baumgarten L, Whale AS, Jones GM, Fernandez-Gonzalez A, Martin J, Foy CA, Alexopoulos P, Huggett JF, Perneczky R. Takousis P, et al. N Biotechnol. 2022 Dec 25;72:97-106. doi: 10.1016/j.nbt.2022.10.001. Epub 2022 Oct 3. N Biotechnol. 2022. PMID: 36202346 Free article.
Development of a highly sensitive liquid biopsy platform to detect clinically-relevant cancer mutations at low allele fractions in cell-free DNA.
Gale D, Lawson ARJ, Howarth K, Madi M, Durham B, Smalley S, Calaway J, Blais S, Jones G, Clark J, Dimitrov P, Pugh M, Woodhouse S, Epstein M, Fernandez-Gonzalez A, Whale AS, Huggett JF, Foy CA, Jones GM, Raveh-Amit H, Schmitt K, Devonshire A, Green E, Forshew T, Plagnol V, Rosenfeld N. Gale D, et al. PLoS One. 2018 Mar 16;13(3):e0194630. doi: 10.1371/journal.pone.0194630. eCollection 2018. PLoS One. 2018. PMID: 29547634 Free PMC article.
International Interlaboratory Digital PCR Study Demonstrating High Reproducibility for the Measurement of a Rare Sequence Variant.
Whale AS, Devonshire AS, Karlin-Neumann G, Regan J, Javier L, Cowen S, Fernandez-Gonzalez A, Jones GM, Redshaw N, Beck J, Berger AW, Combaret V, Dahl Kjersgaard N, Davis L, Fina F, Forshew T, Fredslund Andersen R, Galbiati S, González Hernández Á, Haynes CA, Janku F, Lacave R, Lee J, Mistry V, Pender A, Pradines A, Proudhon C, Saal LH, Stieglitz E, Ulrich B, Foy CA, Parkes H, Tzonev S, Huggett JF. Whale AS, et al. Anal Chem. 2017 Feb 7;89(3):1724-1733. doi: 10.1021/acs.analchem.6b03980. Epub 2017 Jan 18. Anal Chem. 2017. PMID: 27935690
Digital PCR can augment the interpretation of RT-qPCR Cq values for SARS-CoV-2 diagnostics.
Whale AS, von der Heide EK, Kohlenberg M, Brinckmann A, Baedker S, Karalay O, Fernandez-Gonzalez A, Busby EJ, Bustin SA, Hauser H, Missel A, O'Sullivan DM, Huggett JF, Pfaffl MW, Nolan T. Whale AS, et al. Methods. 2022 May;201:5-14. doi: 10.1016/j.ymeth.2021.08.006. Epub 2021 Aug 26. Methods. 2022. PMID: 34454016 Free PMC article.
Procambarus virginalis Lyko, 2017: A new threat to Iberian inland waters.
Sánchez O, Oficialdegui FJ, Torralba-Burrial A, Arbesú R, Valle-Artaza JM, Fernández-González Á, Ardura A, Arias A. Sánchez O, et al. Among authors: fernandez gonzalez a. Ecol Evol. 2024 May 20;14(5):e11362. doi: 10.1002/ece3.11362. eCollection 2024 May. Ecol Evol. 2024. PMID: 38774140 Free PMC article.
168 results